The causal attribution of injury to alcohol consumption: a cross-national meta-analysis from the emergency room collaborative alcohol analysis project.
The causal attribution of injury to alcohol consumption: a cross-national meta-analysis from the emergency room collaborative alcohol analysis project.
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饮酒造成伤害的因果归因：急诊室协作酒精分析项目的跨国荟萃分析。
DOI：
10.1097/01.alc.0000095863.78842.f0
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发表时间：
2003
期刊：
影响因子：
--
通讯作者：
Borges,Guilherme
中科院分区：
文献类型：
--
作者：
Cherpitel,CherylJ;Ye,Yu;Bond,Jason;Borges,Guilherme
背景：虽然大量文献记载了酒精与损伤的关系，但因果关系尚不明确。方法：通过对急诊室协作酒精分析项目（Emergency Room Collaborative Alcohol Analysis Project.Results）中8个国家的13项急诊室研究进行Meta分析，研究了事件中饮酒变量与酒精消费和损伤事件因果关系的关系。结果：急诊室就诊时对数转换的血液酒精浓度和损伤前6小时内饮酒量的合并比值比具有阳性预测性（分别为1.19和1.80），并且在研究中具有异质性。当控制年龄和性别时，效应量变化不大。当在过去一年中报告五次或五次以上饮酒时（每年饮酒5次以上），饮酒量仅对每年饮酒5次以上的饮酒者报告饮酒与伤害的因果关系具有积极预测作用。在控制饮酒量的情况下，受伤时醉酒感的效应量具有正预测性（2.04），但在研究中存在异质性。Meta-分析回归发现，酒精在有害模式中的消耗水平是血液酒精浓度的重要预测因子，并且在受伤时的消耗量和醉酒感，在因果归因上，具有较低的有害模式水平和较大的效应量。急性饮酒与因果归因的关联可能在一定程度上受到慢性饮酒的影响，但这种关联会受到社会有害饮酒模式的程度的负面影响。
Background:Whereas a substantial literature exists documenting the association of alcohol and injuries, causal associations are less well established.Methods:The relationship of drinking‐in‐the‐event variables with attributing a causal association of alcohol consumption and the injury event was examined by using meta‐analysis across 13 emergency room studies from 8 countries included in the Emergency Room Collaborative Alcohol Analysis Project.Results:Pooled odds ratios for both log‐transformed blood alcohol concentration at the time of the emergency room visit and the amount of alcohol consumed in the 6 hr before injury were positively predictive (1.19 and 1.80, respectively) and heterogeneous across studies. Effect size changed little when age and gender were controlled. When stratifying on reporting five or more drinks on an occasion during the last year (5+ yearly drinkers), the amount consumed was positively predictive of reporting a casual association of drinking and injury only for 5+ yearly drinkers. The effect size of feeling drunk at the time of injury, controlling for the amount of alcohol consumed, was positively predictive (2.04) but heterogeneous across studies. Meta‐analysis regression found the level to which alcohol is consumed in a detrimental pattern to be a significant predictor of blood alcohol concentration, and of the amount consumed and feeling drunk at the time of injury, on causal attribution, with a lower detrimental pattern level with a larger effect size.Conclusions:The association of acute use of alcohol on causal attribution may be affected by chronic use to some extent, but this association is negatively affected by the degree to which a society exhibits harmful drinking patterns.