CURRENT FEVER OF UNKNOWN ORIGIN 1982-1992
CURRENT FEVER OF UNKNOWN ORIGIN 1982-1992
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DOI：
10.2169/internalmedicine.33.67
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发表时间：
1994-02-01
影响因子：
1.2
通讯作者：
KASHIWAZAKI, S
中科院分区：
文献类型：
--
作者：
IIKUNI, Y;OKADA, J;KASHIWAZAKI, S
自1961年彼得斯多夫和比森首次严格定义不明原因发热以来，不明原因发热（FUO）一直是一个重大的临床挑战。在这项临床研究中，对153例符合FUO经典标准的患者进行了回顾性研究。胶原血管疾病被发现是FUO最常见的原因，这是自1971年至1982年进行的最后一次研究以来的变化，取代感染成为FUO最常见的疾病类别。对老年患者的FUO进行了分析。通过比较以前记录的研究，我们观察到一个新的变化，疾病是FUO的可能原因。本报告将定义日本FUO的现状，并与我们以前的研究和其他文献研究进行比较，以确定引起FUO的疾病谱的变化。
Since its first rigid definition in 1961 by Petersdorf and Beeson, fever of unknown origin (FUO) has been a major clinical challenge. In this clinical investigation, a retrospective study was conducted on 153 patients meeting the classic criteria of FUO. Collagen-vascular disease was found to be the most common cause of FUO, a change since our last study conducted from 1971 to 1982, replacing infection as the most common disease category of FUO. FUO in elderly patients was also analyzed. By comparing previously documented studies, we observed a new variation in the diseases that are possible causes of FUO. This report will define the present status of FUO in Japan, as well as a comparison with our previous study and other documented studies to determine the shift in the spectrum of diseases causing FUO.