Frontal behavioral and emotional symptoms in Spanish individuals with acquired brain injury and substance use disorders
Frontal behavioral and emotional symptoms in Spanish individuals with acquired brain injury and substance use disorders
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DOI：
10.1016/j.acn.2008.03.004
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发表时间：
2008-07-01
影响因子：
2.6
通讯作者：
Puente, A. E.
中科院分区：
文献类型：
--
作者：
Caracuel, A.;Verdejo-Garcia, A.;Puente, A. E.
简介：获得性脑损伤影响额叶皮质的患者和物质使用障碍患者共同存在一系列行为问题，包括冷漠、自我控制能力差和执行功能障碍。额叶系统行为量表（FrSBe）是一种自我报告工具，旨在测量因额叶-纹状体神经系统损伤而导致的行为问题，涉及脑损伤和成瘾。本研究的目的是双重的：（1）比较分数从西班牙语版本的FrSBe与规范收集的美国，讲英语的人口;和（2）检查的能力FrSBe区分两个临床人群（获得性脑损伤（ABI）和成瘾）与假定的额叶功能障碍，相比，一组，健康的参与者。患者和方法：共有139名志愿者参加了研究，其中包括46名额叶ABI（F-ABI）患者，57名戒断物质滥用者和36名来自西班牙人群的健康对照。西班牙语版的FrSBe管理的所有参与者。我们进行了多变量方差分析，以检查三个分量表的组间差异：冷漠，去抑制和执行功能障碍;和FrSBe总分。结果：F-ABI和物质滥用者得分较高（即，FrSBe总分比对照组受损更大）; F-ABI患者的评分显着高于物质滥用者，物质滥用者显着高于对照组。对于特定的分量表，F-ABI患者有较高的分数比物质滥用者和对照组的冷漠，去抑制和执行功能障碍的分量表，而物质滥用者有更大的执行功能障碍比对照。结论：西班牙语版本的FrSBe是有用的工具，用于检测与额叶系统功能障碍相关的行为问题，在两个临床样本的西班牙语发言者。(C)2008年美国国家神经心理学学会。由爱思唯尔有限公司出版。保留所有权利。
INTRODUCTION: Patients with acquired brain injury affecting the frontal cortex and individuals with substance use disorders share a range of behavioral problems, including apathy, poor self-control, and executive dysfunction. The Frontal Systems Behavioral Scale (FrSBe) is a self-report instrument designed to measure behavioral problems resulting from damage to:the frontal-striatal neural systems, involved both in brain insult and addiction. The aim of this study was twofold: (1) to compare the scores from the Spanish version of the FrSBe with the norms collected for American, English-speaking population; and (2) to examine the ability of the FrSBe to discriminate between two clinical populations (acquired brain injury (ABI) and addiction) with putative frontal dysfunction, as compared to a group,of healthy participants. PATIENTS AND METHODS: A total of 139 volunteers participated including 46 patients with frontal ABI (F-ABI), 57 abstinent substance abusers, and 36 healthy controls from the Spanish population. A Spanish version of the FrSBe was administered to all participants. We conducted multivariate analyses of variance to examine group differences across the three subscales: apathy, disinhibition, and executive dysfunction; and in the FrSBe total score. RESULTS: F-ABI and substance abusers had higher scores (i.e., greater impairment) than controls on the FrSBe total score; F-ABI patients scored significantly higher than substance abusers, and substance abusers significantly higher than controls. For specific subscales, F-ABI patients had higher scores than substance abusers and controls in the subscales of apathy, disinhibition and executive dysfunction, whereas substance abusers had greater executive dysfunction than controls. CONCLUSIONS: The Spanish version of the FrSBe is useful instrument for the detection of behavioral problems associated with frontal systems dysfunction in two clinical samples of Spanish-speakers. (C) 2008 National Academy of Neuropsychology. Published by Elsevier Ltd. All rights reserved.