New insights into glomerular parietal epithelial cell activation and its signaling pathways in glomerular diseases.
New insights into glomerular parietal epithelial cell activation and its signaling pathways in glomerular diseases.
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肾小球疾病中肾小球壁上皮细胞激活及其信号通路的新见解
DOI:
10.1155/2015/318935
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发表时间:
2015
影响因子:
--
通讯作者:
Zhang C
中科院分区:
文献类型:
--
作者:
Su H;Chen S;He FF;Wang YM;Bondzie P;Zhang C
The glomerular parietal epithelial cells (PECs) have aroused an increasing attention recently. The proliferation of PECs is the main feature of crescentic glomerulonephritis; besides that, in the past decade, PEC activation has been identified in several types of noninflammatory glomerulonephropathies, such as focal segmental glomerulosclerosis, diabetic glomerulopathy, and membranous nephropathy. The pathogenesis of PEC activation is poorly understood; however, a few studies delicately elucidate the potential mechanisms and signaling pathways implicated in these processes. In this review we will focus on the latest observations and concepts about PEC activation in glomerular diseases and the newest identified signaling pathways in PEC activation.
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影响因子:
82.9
作者:
通讯作者:
--
影响因子:
5
作者:
Burnworth, Bettina;Pippin, Jeff;Nelson, Peter J.
通讯作者:
Nelson, Peter J.
DOI:
10.1053/j.ajkd.2011.05.032
发表时间:
2011-10
期刊:
American journal of kidney diseases : the official journal of the National Kidney Foundation
影响因子:
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作者:
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Shankland SJ
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Salant DJ
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19.6
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Dijkman, H. B. P. M.;Weening, J. J.;Wetzels, J. F. M.
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Wetzels, J. F. M.