CHARACTERISTICS AND CLASSIFICATION OF TYPE 3 NEOVASCULARIZATION WITH B-SCAN FLOW OVERLAY AND EN FACE FLOW IMAGES OF OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY
CHARACTERISTICS AND CLASSIFICATION OF TYPE 3 NEOVASCULARIZATION WITH B-SCAN FLOW OVERLAY AND EN FACE FLOW IMAGES OF OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY
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DOI：
10.1097/iae.0000000000002357
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发表时间：
2020-01-01
影响因子：
3.3
通讯作者：
Terasaki, Hiroko
中科院分区：
文献类型：
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作者：
Kataoka, Keiko;Takeuchi, Jun;Terasaki, Hiroko
目的：研究3型新生血管（NV）的B扫描血流叠加和表面血流光学相干断层扫描血管造影（OCT-A）图像，并根据OCT-A结果表征3型NV的分期系统。方法：我们回顾性收集了连续的3型NV的治疗初治眼的数据。所有患眼均接受荧光素血管造影、吲哚菁绿色血管造影、结构光谱域OCT和OCT-A（血管造影剂）。对B超血流叠加和正面OCT-A图像检测到的异常血流进行定位和扩展评估。结果如下：在22例3型NV患者的24只眼中，B扫描血流叠加图像显示，4.2%的患者在视网膜深层有毛细血管扩张血流，无外丛状层破坏（第1期），8.3%的患者有视网膜内向下血流和视网膜下血流，无视网膜色素上皮破坏（第2期），87.5%的患者有视网膜下向下血流和视网膜色素上皮破坏（第3期）。在第3阶段的眼睛中，95.2%的显示在B-扫描血流叠加图像上的视网膜色素上皮破裂部位处的血流信号穿透。结论：B超血流叠加和正面OCT-A图像显示了3型NV的特征。B超血流叠加OCT-A图像似乎有助于提高3型NV的检测和准确诊断。
Purpose: To study B-scan flow overlay and en face flow optical coherence tomography angiography (OCT-A) images of Type 3 neovascularization (NV) and to characterize a staging system for Type 3 NV based on the OCT-A findings. Methods: We retrospectively collected data on consecutive treatment-naive eyes with Type 3 NV. All eyes underwent fluorescein angiography, indocyanine green angiography, structural spectral domain OCT, and OCT-A (AngioPlex). Localization and extension of abnormal flows detected by B-scan flow overlay and en face OCT-A images were assessed. Results: Of 24 eyes of 22 patients with Type 3 NV, B-scan flow overlay images showed that 4.2% had telangiectatic flow in the deep retinal layer without outer plexiform layer disruption (Stage 1), 8.3% had downward intraretinal flow and subretinal flow without retinal pigment epithelium disruption (Stage 2), and 87.5% had downward flow and retinal pigment epithelium disruption (Stage 3). Of the Stage 3 eyes, 95.2% showed flow signal penetrating at the site of the retinal pigment epithelium disruption on the B-scan flow overlay images. Conclusion: We showed the characteristics of Type 3 NV using B-scan flow overlay and en face OCT-A images. B-scan flow overlay OCT-A images seem useful to improve the detection and accurate diagnosis of Type 3 NV.