Antimicrobial Activity of Metals and Metalloids.

Antimicrobial Activity of Metals and Metalloids.
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金属和准金属的抗菌活性

DOI:
10.1146/annurev-micro-032921-123231
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发表时间:
2021-10-08
影响因子:
10.5
通讯作者:
Rensing C
Rensing C
中科院分区:
生物学1区
文献类型:
--
作者:
Li YP;Ben Fekih I;Chi Fru E;Moraleda-Munoz A;Li X;Rosen BP;Yoshinaga M;Rensing C

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竞争塑造着进化。自从地球上第一批生物出现以来,有毒金属和类金属对生命施加了选择性压力,这导致了对它们的抵抗机制的进化和获得,以及使它们武器化的机制。微生物利用抗菌金属和类金属来获得相对于微生物群落其他成员的竞争优势。该综述描述了微生物如何利用金属和类金属进行捕食,以及依赖于金属和类金属的捕食可能是微生物对金属和类金属的抗性进化的驱动力。
Competition shapes evolution. Toxic metals and metalloids have exerted selective pressure on life since the rise of the first organisms on the Earth, which has led to the evolution and acquisition of resistance mechanisms against them, as well as mechanisms to weaponize them. Microorganisms exploit antimicrobial metals and metalloids to gain competitive advantage over other members of microbial communities. This exerts a strong selective pressure that drives evolution of resistance.This review describes, with a focus on arsenic and copper, how microorganisms exploit metals and metalloids for predation and how metal- and metalloid-dependent predation may have been a driving force for evolution of microbial resistance against metals and metalloids.
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