Sarcopenia: definition, epidemiology, and pathophysiology.

Sarcopenia: definition, epidemiology, and pathophysiology.
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DOI:
10.11005/jbm.2013.20.1.1
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发表时间:
2013-05
影响因子:
--
通讯作者:
Choi KM
Choi KM
中科院分区:
其他
文献类型:
--
作者:
Kim TN;Choi KM

文献摘要

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我们这一代人的流行病趋势是人口老龄化。衰老会导致肌肉质量和力量的逐渐丧失,这种症状在希腊语中的意思是“肌肉贫乏”。骨质疏松症可能导致功能障碍、身体残疾,甚至死亡。今天,石棺减少是一个巨大的公众关注的问题,以防止衰老。它的患病率继续上升,可能是由于世界各地老年人口不断增加的结果。本文阐述了骨质疏松症的定义、流行病学及其基本的病理生理学。此外,我们还总结了大量有关骨质疏松症的文献资料,以及我们进行的韩国骨质疏松症肥胖研究(KSOS)的结果。
The epidemiological trends that characterize our generation are the aging of the population. Aging results in a progressive loss of muscle mass and strength called sarcopenia, which is Greek for 'poverty of flesh'. Sarcopenia could lead to functional impairment, physical disability, and even mortality. Today, sarcopenia is a matter of immense public concern for aging prevention. Its prevalence continues to rise, probably as a result of increasing elderly populations all over the world. This paper addressed the definition and epidemiology of sarcopenia and its underlying pathophysiology. In addition, we summarized the abundant information available in the literature related to sarcopenia, together with results from Korean sarcopenic obesity study (KSOS) that we performed.