Effect of exercise on 24-month weight loss maintenance in overweight women
Effect of exercise on 24-month weight loss maintenance in overweight women
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DOI：
10.1001/archinte.168.14.1550
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发表时间：
2008-07-28
影响因子：
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通讯作者：
Janney, Carol
中科院分区：
文献类型：
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作者：
Jakicic, John M.;Marcus, Bess H.;Janney, Carol
背景：关于体力活动的多少有助于维持体重的争论仍然存在。方法：1999年12月1日至2003年1月31日，从某医院减肥研究中心招募201名体重超重和肥胖妇女（体重指数[以体重公斤除以身高米的平方计算]，年龄21-45岁），无减肥或体育活动禁忌症。参与者被分配到四个行为减肥干预组中的一个。他们根据体力活动能量消耗（1000 vs 2000千卡/周）和强度（中等vs剧烈）被随机分配到不同的组。参与者还被告知将摄入量减少到每天1200到1500千卡。在24个月的研究期间，进行了面对面交谈和电话交谈的结合。结果：在6个月（初始体重的8%-10%）或24个月（初始体重的5%）的随访中，随机分组的体重减轻没有差异。事后分析显示，在24个月时体重减少10%或更多的个体报告的体力活动（1835千卡/周或275分钟/周）比体重减少不到10%的个体多（P < 0.001）。结论：增加275分钟/周的体力活动，结合减少能量摄入，对于让超重女性维持10%以上的体重减轻很重要。需要采取干预措施促进这种水平的身体活动。试验注册：clinical trials.gov标识符：NCT00006315。
Background: Debate remains regarding the amount of physical activity that will facilitate weight loss maintenance.Methods: Between December 1, 1999, and January 31, 2003, 201 overweight and obese women (body mass index [calculated as weight in kilograms divided by height in meters squared], 27 to 40; age range, 21-45 years) with no contraindications to weight loss or physical activity were recruited from a hospital-based weight loss research center. Participants were assigned to 1 of 4 behavioral weight loss intervention groups. They were randomly assigned to groups based on physical activity energy expenditure (1000 vs 2000 kcal/wk) and intensity (moderate vs vigorous). Participants also were told to reduce intake to 1200 to 1500 kcal/d. A combination of in-person conversations and telephone calls were conducted during the 24-month study period.Results: Weight loss did not differ among the randomized groups at 6 months'(8%-10% of initial body weight) or 24 months' (5% of initial body weight) follow-up. Post-hoc analysis showed that individuals sustaining a loss of 10% or more of initial body weight at 24 months reported performing more physical activity (1835 kcal/wk or 275 min/wk) compared with those sustaining a weight loss of less than 10% of initial body weight (P < .001).Conclusions: The addition of 275 mins/wk of physical activity, in combination with a reduction in energy intake, is important in allowing overweight women to sustain a weight loss of more than 10%. Interventions to facilitate this level of physical activity are needed.Trial Registration: clinical trials.gov Identifier: NCT00006315.