Biochemical markers in rats: linkage relationships of aconitase (Acon-1), aldehyde dehydrogenases (Ahd-2 and Ahd-c), alkaline phosphatase (Akp-1), and hydroxyacid oxidase (Hao-1).
Biochemical markers in rats: linkage relationships of aconitase (Acon-1), aldehyde dehydrogenases (Ahd-2 and Ahd-c), alkaline phosphatase (Akp-1), and hydroxyacid oxidase (Hao-1).
复制标题
大鼠生化标志物：乌头酸酶（Acon-1）、醛脱氢酶（Ahd-2和Ahd-c）、碱性磷酸酶（Akp-1）和羟酸氧化酶（Hao-1）的连锁关系。
DOI：
10.1007/bf00502790
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发表时间：
1986
影响因子：
2.4
通讯作者：
Adams,M
中科院分区：
文献类型：
--
作者：
Cramer,DV;Mowery,PA;Adams,M
我们在5个育种组合中检测了5个生化标记Acon-1、Ahd-2、Ahd-c、Akp-1和Hao-1与19个其它遗传位点之间的连锁关系。编码最近描述的肝脏中的醛脱氢酶（Ahd-c）的遗传位点已被分配到连锁群X（LG X）。羟酸氧化酶是由一个位点（Hao-1）编码的，该位点与连锁群IV中编码蛋白质和精囊蛋白质的基因连锁。碱性磷酸酶（Akp-1）与编码补体C6组分的基因座相连，这种关联暂时定义了大鼠中的一个新的连锁群（LG XI）。Acon-1位点不能被正向分配到一个特定的连锁群，但从一个育种组合的结果表明，该位点可能包括在连锁群II。Ahd-2编码的乙醛脱氢酶没有连锁关系。
We have examined the linkage relationships between five biochemical markers,Acon-1, Ahd-2, Ahd-c, Akp-1, andHao-1, and 19 other genetic loci in five breeding combinations. The genetic locus that codes for a recently described aldehyde dehydrogenase in the liver(Ahd-c)has been assigned to linkage group X (LG X). Hydroxyacid oxidase is coded for by a locus(Hao-1)that is linked to genes that encode agouti coat color and seminal vesicle proteins in linkage group IV. Alkaline phosphatase(Akp-1)was linked to the locus that encodes the C6 component of complement and this association provisionally defines a new linkage group (LG XI) in the rat. The locusAcon-1could not be positively assigned to a specific linkage group but the results from one breeding combination suggest that this locus may be included in linkage group II. No linkage relationship could be detected for the aldehyde dehydrogenase coded for byAhd-2.