Alcohol consumption and total mortality/morbidity - definitions and methodological implications
Alcohol consumption and total mortality/morbidity - definitions and methodological implications
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DOI：
10.1016/s1521-6918(03)00032-5
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发表时间：
2003-08-01
影响因子：
3.2
通讯作者：
Gmel, G
中科院分区：
文献类型：
--
作者：
Rehm, J;Gmel, G
关于酒精消费和总死亡率/发病率的研究有两种主要类型，即：个体水平研究和总体水平研究。酒精消费通常以数量或平均消费量为特征。最近，饮酒的模式，特别是酗酒的场合，已经被引入。在个人层面上，死亡率的定义是微不足道的（死亡），发病率的定义要么是住院治疗，要么是主观定义。在总体上，死亡率以死亡率或丧失生命年数来定义，发病率以住院率或因残疾丧失生命年数来定义。残疾调整生命年（DALYs）将死亡率和发病率结合为健康的综合衡量标准。在评估酒精与结果之间的关系时，个人水平的研究显然应该优先考虑，只要酒精消费评估是最先进的，样本包括所有相关的饮酒模式，再加上对混杂因素有充分的控制和充分的统计分析。
Two main types of studies of alcohol consumption and total mortality/morbidity are distinguished, namely: individual level studies and aggregate level studies.Alcohol consumption is usually characterized in terms of volume or average volume of consumption. More recently, patterns of drinking, especially heavy drinking occasions, have been introduced. On the individual level, the definition of mortality is trivial (death) and morbidity is either defined by hospitalization or by subjective definitions. On the aggregate level, mortality is defined either in death rates or in years of life lost, and morbidity as hospitalization rates or years of life lost to disability. Disability Adjusted Life Years (DALYs) combine mortality and morbidity into a summary measure of health.Individual level studies clearly should be given preference in assessing the relationship between alcohol and outcomes, as long as the assessment of alcohol consumption is state-of-the-art and the sample includes all relevant drinking patterns, plus if there is adequate control for confounding and adequate statistical analysis.