The impact of high apparent temperature on spontaneous preterm delivery: a case-crossover study.
The impact of high apparent temperature on spontaneous preterm delivery: a case-crossover study.
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DOI：
10.1186/s12940-017-0209-5
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发表时间：
2017-02-01
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影响因子：
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通讯作者：
Basu R
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作者：
Avalos LA;Chen H;Li DK;Basu R
尽管预测未来气温预计会上升，但人们对气温上升对孕妇健康的影响知之甚少。本研究的目的是调查表观温度对自发性早产（PTD）的影响。对1995年1月1日至2009年12月31日期间在Kaiser Permanente北方加州（KPNC）成员中发生的14，466例单胎自发早产进行了病例交叉研究。通过KPNC的电子健康记录（EHR）数据确定早产。分娩时的胎龄、婴儿性别和母亲地址的数据也从KPNC的EHR中提取，并与基于住宅邮政编码的气象和空气污染监测数据相关联。在温暖季节，自发PTD增加11.6%（95%CI：4.1，19.7）与每周平均（lag 06）表观温度增加10 °F（5.6 °C）相关。在寒冷季节，表观温度的升高对自发PTD的总体效应没有显著影响（每周平均（lag 06）表观温度每升高10 °F（5.6 °C），自发PTD的总体效应为6.2%，（95%CI：-3.0，16.2））。在寒冷季节，表观温度与自发PTD之间的关系因地区、胎龄和婴儿性别而存在显著差异。空气污染物没有明显差异。我们的研究结果提供的证据表明，自发性PTD的几率增加与表观温度的增加，特别是在温暖的季节。本文的在线版本（doi：10.1186/s12940-017-0209-5）包含补充材料，可供授权用户使用。
Despite the prediction that temperatures are expected to increase in the future, little is known about the health effects of increasing temperatures on pregnant women. The objective of this study was to investigate the impact of apparent temperature on spontaneous preterm delivery (PTD). A case-crossover study of 14,466 singleton spontaneous preterm deliveries occurring between January 1, 1995 and December 31, 2009 among Kaiser Permanente Northern California (KPNC) members was conducted. Preterm deliveries were identified through KPNC's Electronic Health Records (EHR) data. Data on gestational age at delivery, infant sex, and maternal address were also extracted from KPNC's EHR and linked to meteorologic and air pollution monitoring data based on residential zip code. An 11.6% (95% CI: 4.1, 19.7) increase in spontaneous PTD was associated with a 10 °F (5.6 °C) increase in weekly average (lag06) apparent temperature, during the warm season. During the cold season, increases in apparent temperature did not significantly impact the overall effect of spontaneous PTD (6.2%, (95% CI: -3.0, 16.2) per 10 °F (5.6 °C) increase in weekly average (lag06) apparent temperature). Significant differences in the relationship between apparent temperature and spontaneous PTD emerged for region, gestational age and infant sex, during the cold season. No significant differences emerged for air pollutants. Our findings provide evidence for an increase in the odds of spontaneous PTD associated with increases in apparent temperature, especially during the warm season. The online version of this article (doi:10.1186/s12940-017-0209-5) contains supplementary material, which is available to authorized users.