Flow Cytometric Immunophenotypic Analysis in the Diagnosis and Prognostication of Plasma Cell Neoplasms

Flow Cytometric Immunophenotypic Analysis in the Diagnosis and Prognostication of Plasma Cell Neoplasms
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流式细胞术免疫表型分析在浆细胞肿瘤的诊断和预后中的应用

DOI:
10.1002/cyto.b.21844
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发表时间:
2019
期刊:
Cytometry Part B: Clinical Cytometry
影响因子:
--
通讯作者:
P. Lin
P. Lin
中科院分区:
--
文献类型:
--
作者:
Hao‐Wei Wang;P. Lin

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本文综述了流式细胞术免疫表型在浆细胞肿瘤鉴别诊断和治疗后监测微小(可测量)残留病变中的作用。需要整合流式细胞术的数据与临床,实验室,放射学,形态学和分子遗传学的研究结果强调。还强调了在靶向治疗的背景下评估浆细胞的挑战和策略。© 2019国际临床细胞计数学会
This review focuses on the roles of flow cytometric immunophenotyping has in the differential diagnosis of plasma cell neoplasms and the post‐therapy monitoring of minimal (measurable) residual disease. The need to integrate flow cytometry data with clinical, laboratory, radiographic, morphological, and molecular genetic findings is emphasized. The challenges of and strategies for evaluating plasma cells in the setting of targeted therapy are also highlighted. © 2019 International Clinical Cytometry Society
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