Phosphonium Ionic Liquid-Infused Poly(vinyl chloride) Surfaces Possessing Potent Antifouling Properties
Phosphonium Ionic Liquid-Infused Poly(vinyl chloride) Surfaces Possessing Potent Antifouling Properties
复制标题
DOI：
10.1021/acsomega.9b03528
复制
发表时间：
2020-04
期刊：
影响因子：
4.1
通讯作者：
M. Wylie;S. Bell;P. Nockemann;Rory Bell;C. McCoy
中科院分区：
文献类型：
--
作者：
M. Wylie;S. Bell;P. Nockemann;Rory Bell;C. McCoy
微生物结垢是一个代价高昂的问题，其影响广泛的行业，例如医疗保健、食品加工和建筑行业，并且迫切需要改进的策略来减少结垢的影响。最近开发了一种生物启发的方法，以防止滑动液体注入多孔表面（SLIPS）。在这里，我们报告的发展光滑，超亲水性表面注入粗糙的聚氯乙烯（PVC）基板与磷离子液体（PIL）。相对于对照PVC，在静态条件下24 h后，这些表面能够将金黄色葡萄球菌和铜绿假单胞菌的活菌粘附减少>6 log 10 cfu mL-1。此外，我们报告了一系列具有不同烷基链长（C4-C18）和抗衡阴离子的不对称季烷基PIL作为抗革兰氏阳性菌和革兰氏阴性菌的抗菌剂的潜力，并说明了它们作为SLIPS合成中常用的传统氟化润滑剂的抗菌替代品的潜力。
Microbial fouling is a costly issue, which impacts a wide range of industries, such as healthcare, food processing, and construction industries, and improved strategies to reduce the impact of fouling are urgently required. Slippery liquid-infused porous surfaces (SLIPSs) have recently been developed as a bioinspired approach to prevent antifouling. Here, we report the development of slippery, superhydrophilic surfaces by infusing roughened poly(vinyl chloride) (PVC) substrates with phosphonium ionic liquids (PILs). These surfaces were capable of reducing viable bacterial adherence by Staphylococcus aureus and Pseudomonas aeruginosa by >6 log10 cfu mL–1 after 24 h under static conditions relative to control PVC. Furthermore, we report the potential of a series of asymmetric quaternary alkyl PILs with varying alkyl chain lengths (C4–C18) and counteranions to act as antimicrobial agents against both Gram +ve and Gram −ve bacteria and illustrate their potential as antimicrobial alternatives to traditional fluorinated lubricants commonly used in the synthesis of SLIPSs.