Cognitive reserve and working memory in cognitive performance of adults with subjective cognitive complaints: longitudinal structural equation modeling
Cognitive reserve and working memory in cognitive performance of adults with subjective cognitive complaints: longitudinal structural equation modeling
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DOI：
10.1017/s1041610219001248
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发表时间：
2020-04-01
影响因子：
7
通讯作者：
Juncos-Rabadan, Onesimo
中科院分区：
文献类型：
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作者：
Lojo-Seoane, Cristina;Facal, David;Juncos-Rabadan, Onesimo
目的：探讨认知储备对36个月内有主观认知主诉者认知能力的影响。设计：我们使用了一个一般的线性模型重复测量程序来分析三个评估之间的性能差异。我们使用纵向结构方程模型来分析CR与基线和两次随访评估时的认知表现之间的关系。背景：SCC参与者在初级保健中心招募和评估。参与者：共212名年龄大于50岁的SCC参与者。测量：认知储备数据收集与一个特设的问卷调查管理的主题在采访中。对一般认知表现（GCP）、情景记忆（EM）和工作记忆（WM）进行了评价。采用简易精神状态检查量表和西班牙语版剑桥认知功能检查量表的总分对GCP进行评价。情景记忆采用西班牙语版的加州言语学习量表进行评估。工作记忆采用计数广度任务和听力广度任务。结果如下：所提出的模型的满意拟合证实了CR在基线时对WM和GCP的直接影响，以及在第一次和第二次随访时对EM和WM的间接影响。随着时间的推移，观察到CR通过WM对其他认知结构的间接影响。结论：所提出的模型是有用的测量随着时间的推移CR对认知性能的影响。终生获得的认知反应可能影响老年人的认知表现，防止认知退化，从而通过工作记忆增加加工资源。
Objective: To study the influence of cognitive reserve (CR) on cognitive performance of individuals with subjective cognitive complaints (SCCs) within a period of 36 months. Design: We used a general linear model repeated measures procedure to analyze the differences in performance between three assessments. We used a longitudinal structural equation modeling to analyze the relationship between CR and cognitive performance at baseline and at two follow-up assessments. Setting: Participants with SCCs were recruited and assessed in primary care health centers. Participants: A total of 212 participants older than 50 years with SCCs. Measurements: Cognitive reserve data were collected with an ad hoc questionnaire administered to the subjects in an interview. General cognitive performance (GCP), episodic memory (EM), and working memory (WM) have been evaluated. The Mini-Mental State Examination and the total score of Spanish version of the Cambridge Cognitive Examination evaluated the GCP. Episodic memory was assessed with the Spanish version of the California Verbal Learning. Working memory was evaluated by the counting span task and the listening span task. Results: The satisfactory fit of the proposed model confirmed the direct effects of CR on WM and GCP at baseline, as well as indirect effects on EM and WM at first and second follow-up. Indirect effects of CR on other cognitive constructs via WM were observed over time. Conclusion: The proposed model is useful for measuring the influence of CR on cognitive performance over time. Cognitive response acquired throughout life may influence cognitive performance in old age and prevent cognitive deterioration, thus increasing processing resources via WM.