NEW EXPERIMENTAL-MODEL FOR THE EVALUATION OF ADAPTOGENIC PRODUCTS
NEW EXPERIMENTAL-MODEL FOR THE EVALUATION OF ADAPTOGENIC PRODUCTS
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DOI：
10.1016/0378-8741(90)90038-u
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发表时间：
1990-07-01
影响因子：
5.4
通讯作者：
SRIVASTAVA, KK
中科院分区：
文献类型：
--
作者：
RAMACHANDRAN, U;DIVEKAR, HM;SRIVASTAVA, KK
描述了一种新的动物模型，用于评估在不利环境中体力劳动性能和耐力的改善。在该模型中，将束缚的大鼠暴露于5 ℃至480 mmHg大气压。将结果与被迫在23 ℃水中游泳的动物进行比较。C.在两种模型中，在暴露于不利环境期间和在32 ℃和正常大气压下恢复期间连续监测大鼠的结肠温度（Tr）。Tr下降到23 ℃和恢复到37 ℃的时间和模式被用作耐久性的量度。与冷游泳模型相比，耐冷缺氧模型提供了更精确的结果。人参根和银杏叶提取物进行了比较，其积极的促排性能，使用两种模型。
A new animal model for evaluating improvement in physical work performance and endurance in an adverse environment is described. In this model, rats in restraint were exposed to 5.degree.C to 480 mmHg atmospheric pressure. Results were compared to an animal forced to swim in water at 23.degree. C. In both the models, colonic temperature (Tr) of the rats was continually monitored during exposure to adverse environment and during recovery at 32.degree.C and normal atmospheric pressure. The time and pattern for Tr fall to 23.degree.C and its recovery to 37.degree.C were used as measures of endurance. The cold-hypoxia-resistant model was found to provide more precise results compared with the cold-swimming model. Panax ginseng root and Ginkgo biloba leaf extracts were compared for their positive endurance-promoting properties using both models.