Does human mtDNA recombine?
Does human mtDNA recombine?
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DOI：
10.1007/s002390010232
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发表时间：
2001-10-01
影响因子：
3.9
通讯作者：
Awadalla, P
中科院分区：
文献类型：
--
作者：
Eyre-Walker, A;Awadalla, P
本文综述了支持和反对人类mtDNA重组的证据。如果发生重组，就需要有一种途径使遗传物质能够整合到线粒体基因组中，从而在线粒体谱系之间整合。我们回顾了可能途径的证据，然后回顾了重组群体遗传证据的现状。我们得出的结论是，没有确定的重组途径可以发生，虽然一些群体遗传证据暗示了重组，但还远远没有定论。
In this article we review the evidence for and against recombination in human mtDNA. If recombination occurs, there needs to be a route by which genetic material can incorporate itself into the mitochondrial genome, and hence between mitochondrial lineages. We review the evidence for possible routes and then review the current state of the population genetic evidence for recombination. We conclude that there is no firmly established route by which recombination can occur, and that while some of the population genetic evidence is suggestive of recombination, it is far from conclusive.