SYSTOLIC AND DIASTOLIC ABNORMALITIES OF LEFT VENTRICLE IN CORONARY ARTERY DISEASE - STUDIES IN PATIENTS W2TH LITTLE OR NO ENLARGEMENT OF VENTRICULAR VOLUME
SYSTOLIC AND DIASTOLIC ABNORMALITIES OF LEFT VENTRICLE IN CORONARY ARTERY DISEASE - STUDIES IN PATIENTS W2TH LITTLE OR NO ENLARGEMENT OF VENTRICULAR VOLUME
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DOI：
10.1161/01.cir.42.2.219
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发表时间：
1970-01-01
期刊：
影响因子：
37.8
通讯作者：
JUDKINS, MP
中科院分区：
文献类型：
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作者：
BRISTOW, JD;VANZEE, BE;JUDKINS, MP
对15例经冠状动脉造影证实的冠心病（CAD）患者和5例对照组进行60帧/秒的电影心血管造影，计算左室容积和周长。CAD患者无二尖瓣返流，平均舒张末期容积与正常人和对照组相当。CAD患者的平均舒张末期压较高，尽管舒张末期容积没有增加，但通常异常。CAD组的射血率较低，周向纤维缩短的程度也较低。最大和平均纤维缩短率与射血分数呈正相关，并在一些人与CAD.We得出结论，我们的患者没有显着增加左心室舒张末期容积舒张顺应性和收缩性能的异常。
Left ventricular volume and circumference were calculated from cineangiocardiograms at 60 frames/sec in 15 patients with arteriographically proven coronary artery disease (CAD) and five control subjects. The patients with CAD had no mitral regurgitation and had an average end-diastolic volume equivalent to that reported by others in normal subjects and to that of the control group. The average end-diastolic pressure was higher in CAD and was often abnormal, despite lack of increase in enddiastolic volume. The ejection was lower in the CAD group as was the extent of circumferential fiber shortening. Maximal and mean rates of fiber shortening correlated positively with ejection fraction and were low in some individuals with CAD.We conclude that our patients without significant increase in left ventricular enddiastolic volume had abnormalities of diastolic compliance and contractile performance.