Links between environment, diet, and the hunter-gatherer microbiome

Links between environment, diet, and the hunter-gatherer microbiome
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DOI:
10.1080/19490976.2018.1494103
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发表时间:
2019-01-01
期刊:
影响因子:
12.2
通讯作者:
Sonnenburg, Justin L.
Sonnenburg, Justin L.
中科院分区:
医学2区
文献类型:
--
作者:
Fragiadakis, Gabriela K.;Smits, Samuel A.;Sonnenburg, Justin L.

文献摘要

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对传统种群的研究提供了对不受工业化干扰的与人类相关的微生物的看法,以及了解与人类共同进化的微生物群的窗口。在这里,我们讨论我们最近对坦桑尼亚哈扎狩猎采集者微生物群特征的研究。我们发现微生物群的细菌分类群、多样性和碳水化合物利用存在季节性变化。与世界各地其他人群的微生物群组成相比,哈扎人微生物群与其他传统社会共享细菌家族,而这些细菌家族在工业化国家的微生物群中很少或不存在。我们提出了对哈扎人微生物群及其生活方式和环境的额外观察结果,包括在手、水和动物来源上检测到的微生物,微生物群如何随性别和年龄变化,以及将农产品引入饮食的短期影响。在我们之前发表的研究结果和这些额外观察的背景下,我们讨论了未来工作的前进道路。
The study of traditional populations provides a view of human-associated microbes unperturbed by industrialization, as well as a window into the microbiota that co-evolved with humans. Here we discuss our recent work characterizing the microbiota from the Hadza hunter-gatherers of Tanzania. We found seasonal shifts in bacterial taxa, diversity, and carbohydrate utilization by the microbiota. When compared to the microbiota composition from other populations around the world, the Hadza microbiota shares bacterial families with other traditional societies that are rare or absent from microbiotas of industrialized nations. We present additional observations from the Hadza microbiota and their lifestyle and environment, including microbes detected on hands, water, and animal sources, how the microbiota varies with sex and age, and the short-term effects of introducing agricultural products into the diet. In the context of our previously published findings and of these additional observations, we discuss a path forward for future work.