Does a U-shaped relationship exist between alcohol use and DSM-III-R mood and anxiety disorders?
Does a U-shaped relationship exist between alcohol use and DSM-III-R mood and anxiety disorders?
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DOI：
10.1016/j.jad.2002.12.001
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发表时间：
2004-10-01
影响因子：
6.6
通讯作者：
Stein, MB
中科院分区：
文献类型：
--
作者：
Sareen, J;McWilliams, L;Stein, MB
背景资料：在最近的社区调查中，戒酒者和重度饮酒者报告的情绪和焦虑症状比中度饮酒者更多（U形关系）。本研究旨在通过结构化诊断访谈评估情绪和焦虑障碍来调查这种潜在的U形关系，从而扩展这一发现。研究方法：数据来自两个同期的调查，全国科摩罗调查（NCS; N=6780）和安大略健康调查（OHS-MHS; N=7001）的心理健康补充。密歇根大学修订的复合国际诊断访谈（UM-CIDI）被用来在两次调查中进行DSM-III-R精神病诊断。三个相互排斥的终生饮酒类别进行了比较：（1）酒精戒断者-个人报告没有饮酒或少于12个饮酒在任何一年在他们的生活。(2)适度饮酒者-不符合戒酒者或问题饮酒者标准的个人。(3)问题饮酒者-DSM-III-R终生酒精滥用、依赖或危险水平的酒精使用。结果如下：在控制了人口统计学变量后，与适度饮酒者相比，戒酒者的情绪和焦虑障碍发生率并没有显着增加。然而，问题饮酒与情绪和焦虑症显著相关。结论：在这两项调查中，没有证据表明终生饮酒与终生情绪和焦虑症之间存在U型关系。(C)2003 Elsevier B. V.保留所有权利。
Background: In recent community surveys, abstainers and heavy drinkers of alcohol have reported more mood and anxiety symptoms than moderate drinkers (U-shaped relationship). The present study was aimed at extending this finding by investigating this potential U-shaped relationship using structured diagnostic interviews to assess mood and anxiety disorders. Methods: Data came from two contemporaneous surveys, the National Comorbidity Survey (NCS; N=6780) and the Mental Health Supplement of the Ontario Health Survey (OHS-MHS; N=7001). The University of Michigan Revision of the Composite International Diagnostic Interview (UM-CIDI) was used to make DSM-III-R psychiatric diagnoses in both surveys. Three mutually exclusive lifetime alcohol use categories were compared: (1) Alcohol abstainers-individuals reporting no alcohol use or less than 12 drinks in any year throughout their life. (2) Moderate drinkers-individuals that did not meet criteria for alcohol abstainers or problem drinkers. (3) Problem drinkers-DSM-III-R lifetime alcohol abuse, dependence or hazardous levels of alcohol use. Results: After controlling for demographic variables, alcohol abstainers were not found to have significantly higher rates of mood and anxiety disorders in comparison with moderate drinkers. However, problem drinking was significantly associated with mood and anxiety disorders. Conclusions: Across both surveys, there was no evidence of a U-shaped relationship between lifetime alcohol consumption and lifetime mood and anxiety disorders. (C) 2003 Elsevier B.V. All rights reserved.