Psychosocial predictors of the onset of anxiety disorders in women: Results from a prospective 3-year longitudinal study

Psychosocial predictors of the onset of anxiety disorders in women: Results from a prospective 3-year longitudinal study
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DOI:
10.1016/j.janxdis.2009.07.022
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发表时间:
2009-12-01
影响因子:
10.3
通讯作者:
Harlow, Bernard L.
Harlow, Bernard L.
中科院分区:
医学2区
文献类型:
--
作者:
Calkins, Amanda W.;Otto, Michael W.;Harlow, Bernard L.

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在一项前瞻性的、纵向的、基于人口的研究中,我们对643名参与哈佛情绪和周期研究的女性进行了研究,探讨了心理社会变量是否能预测焦虑症的新发或复发。通过结构化临床访谈,在3年内每6个月评估一次焦虑障碍的存在。在有新的焦虑发作的个体中,我们证实了以前的研究结果,即焦虑史,焦虑敏感性增加(对焦虑相关感觉的恐惧)和神经质增加是显着的预测因素。我们还发现,趋势水平支持自信作为焦虑发作的预测因子。然而,在这些变量中,只有焦虑史和焦虑敏感性提供了独特的预测。我们没有发现证据表明消极生活事件作为焦虑发作的预测因素,无论是单独还是与素质压力模型中的其他变量相互作用。这些结果从一个前瞻性的纵向研究进行了讨论,在初级或复发预防工作的潜在作用,这些预测。(C)2009爱思唯尔有限公司保留所有权利。
In a prospective, longitudinal, poulation-based study of 643 women participating in the Harvard Study of Moods and Cycles we examined whether psychosocial variables predicted a new or recurrent onset of an anxiety disorder. Presence of anxiety disorders was assessed every 6 months over 3 years via Structured clinical interviews. Among individuals who had a new episode of anxiety, we confirmed previous findings that history of anxiety, increased anxiety sensitivity (the fear of anxiety related sensations), and increased neuroticism were significant predictors. We also found trend level support for assertiveness as a predictor of anxiety onset. However, of these variables, only history of anxiety and anxiety sensitivity provided unique prediction. We did not find evidence for negative life events as a predictor of onset of anxiety either alone or in interaction with other variables in a diathesis-stress model. These findings from a prospective longitudinal study are discussed in relation to the potential role of such predictors in primary or relapse prevention efforts. (C) 2009 Elsevier Ltd. All rights reserved.