An endodextranase inhibitor from batch cultures of streptococcus mutans.
An endodextranase inhibitor from batch cultures of streptococcus mutans.
复制标题
来自变形链球菌分批培养物的内葡聚糖酶抑制剂。
DOI：
10.1016/0006-291x(82)91792-2
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发表时间：
1982
影响因子：
3.1
通讯作者：
McCabe,MM
中科院分区：
文献类型：
--
作者：
Hamelik,RM;McCabe,MM
通过g -亲和层析法，从代表血清型a的S.，变形链球菌菌株的批培养中制备的蛋白质中检测到一种内生葡聚糖酶抑制剂。菌株6715-49的蛋白质显然不具有内生葡聚糖酶活性，结果发现了一种活性的内生葡聚糖酶，并在单独的峰上发现了内生葡聚糖酶抑制剂。培养基中抑制剂的存在解释了批量培养的S.，已知产生这种酶的突变体中缺乏内酯葡聚糖酶活性。
An inhibitor of Streptococcus, mutans endodextranase was detected in proteins prepared from batch cultures of S., mutans strains representing serotypes a through g. Affinity chromatography of strain 6715-49 proteins, which apparently were free of endodextranase activity, yielded an active endodextranase and, in a separate peak, the endodextranase inhibitor. The presence of the inhibitor in culture fluids accounts for the absence of endodextranase activity in batch-grown cultures of S., mutans known to produce this enzyme.