Risk factors for Toxoplasma gondii infection in women of childbearing age
Risk factors for Toxoplasma gondii infection in women of childbearing age
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DOI：
10.1590/s1413-86702004000200007
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发表时间：
2004-04-01
影响因子：
3.4
通讯作者：
Castro, Ana Maria de
中科院分区：
文献类型：
--
作者：
Avelino, Mariza Martins;Campos Júnior, Dioclécio;Castro, Ana Maria de
目的：确定弓形虫病传播的危险因素，并确定怀孕是否是弓形虫病感染的危险因素。研究设计：对2,242名育龄妇女进行横断面研究。采用间接免疫荧光法检测弓形虫抗体。以前的妊娠也被分析为可能的风险因素。结果用卡方检验、OR检验和方差分析进行统计学处理。根据社会经济风险factors.RESULTS：以前怀孕的妇女感染弓形虫病的频率是1.74倍，无论环境条件。生活在不利环境条件下的孕妇，每种风险因素（与宿主动物接触、存在卵囊传播媒介）的感染风险增加约两倍。以前怀孕的危险因素，获得弓形虫病（方差分析和统计平衡）的影响最大的讨论：这种人畜共患病的患病率高，在戈亚尼亚，GO，巴西（65.8%）。不适当的环境卫生与弓形虫感染没有显着相关性，除了当与以前的怀孕，表明感染的根本原因是不是environmental.CONCLUSION：发现怀孕使妇女更容易受到这种原生动物，重要的是要实施预防性控制的高危孕妇。
OBJECTIVES: Determine the risk factors involved in toxoplasmosis transmission and determine whether pregnancy is a risk factor for toxoplasmosis infection.STUDY DESIGN: Cross-sectional study carried out on 2,242 women at childbearing age. An indirect immunofluorescence reaction was used to identify immunity to Toxoplasma gondii. Previous gestations were also analyzed as a possible risk factor. The results were analyzed by chi2 and OR tests, and by variance analysis. The sample was statistically balanced according to social-economic risk factors.RESULTS: Previously pregnant women were 1.74 times more frequently infected with toxoplasmosis, regardless of environmental conditions. Pregnant women living under unfavorable environmental conditions had an approximately two times increased risk of being infected for each risk factor (contact with host animals, presence of vehicles of oocyst transmission). Previous pregnancy was the risk factor that had the strongest influence on acquiring toxoplasmosis (variance analysis and statistical balancing).DISCUSSION: The prevalence of this zoonosis is high in Goiania-GO, Brazil (65.8%). Inadequate environmental sanitation was not significantly correlated with toxoplasmosis infection, except when associated with previous pregnancy, showing that the fundamental cause for infection is not environmental.CONCLUSION: The finding that pregnancy makes women more vulnerable to this protozoan, makes it important to implement prophylactic control of at-risk pregnant women.