The detection of subclinical synovitis by ultrasound in oligoarticular juvenile idiopathic arthritis: a pilot study
The detection of subclinical synovitis by ultrasound in oligoarticular juvenile idiopathic arthritis: a pilot study
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DOI：
10.1093/rheumatology/kep339
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发表时间：
2010-01-01
期刊：
影响因子：
5.5
通讯作者：
Wakefield, Richard J.
中科院分区：
文献类型：
--
作者：
Haslam, Kirsty E.;McCann, Liza J.;Wakefield, Richard J.
目标.成人研究表明，超声检查（US）在检测滑膜炎方面比临床检查更敏感。亚临床疾病的检测对于决定哪些患者从一开始就接受更积极的治疗具有重要意义。本研究旨在确定临床诊断为少关节型幼年特发性关节炎（JIA）的儿童是否存在超声可检测到的亚临床滑膜炎。这是一项在三级儿科风湿病诊所进行的横断面初步研究。17名儿童，中位年龄为10岁（范围3-13岁），持续存在少关节疾病
Objectives. Adult studies have demonstrated that ultrasonography (US) is more sensitive at detecting synovitis than clinical examination. The detection of subclinical disease has implications for deciding which patients receive more aggressive therapy from the outset. This study aimed to determine whether children with clinically diagnosed oligoarticular juvenile idiopathic arthritis (JIA) had US-detectable subclinical synovitis.Methods. This was a cross-sectional pilot study conducted in a tertiary paediatric rheumatology clinic. Seventeen children with a median age of 10 years (range 3-13 years) and with oligoarticular disease of duration