Comparison of optical quality metrics to predict subjective quality of vision after laser in situ keratomileusis
Comparison of optical quality metrics to predict subjective quality of vision after laser in situ keratomileusis
复制标题
DOI：
10.1016/j.jcrs.2008.12.039
复制
发表时间：
2009-05-01
影响因子：
2.8
通讯作者：
Kohnen, Thomas
中科院分区：
文献类型：
--
作者：
Buehren, Jens;Pesudovs, Konrad;Kohnen, Thomas
目的：比较波前测量在预测准分子激光原位角膜磨镶术(LASIK)术后主观视觉质量方面的作用。研究对象：德国美因河畔法兰克福歌德大学眼科。方法：术后1个月，采用问卷调查的方法，对3种照明条件(明视、高度中视、低度中视)进行波前感知，并进行主观视觉质量评估。对于瞳孔直径为6.0 mm和个人生理瞳孔直径为0.4lux的情况，计算了四种波前误差表示：(1)基于光学传递函数(VSOTF)的视觉Strehl比，(2)Zernike阶数2到5的均方根值(RMS)，(3)高阶像差(HOA)RMS，和(4)波前误差分解为低阶像差、彗差、球面像差和剩余HOA的RMS。用线性回归分析计算术后波前误差对主观视觉质量的影响。结果：纳入患者29例56眼。基于波前误差的测量方法预测主观视觉质量的能力有限。根据矫正最好的眼睛计算的VSOTF显示出最高的可预测性。计算个别生理瞳孔直径的波前误差并不能提高测量的预测能力。理论视网膜图像质量高者主观视觉质量高，主观视觉质量低者理论图像质量低。结论：术后波前误差对主观视觉质量的影响有限。术后应尽可能保持较高的视网膜图像质量，以提供良好的主观视觉质量。
PURPOSE: To compare wavefront-derived metrics to predict subjective quality of vision after laser in situ keratomileusis (LASIK) for myopia.SETTING: Department of Ophthalmology, Goethe University, Frankfurt am Main, Germany.METHODS: One month postoperatively, wavefront sensing was performed and overall subjective quality of vision assessed under 3 lighting conditions (photopic, high mesopic, low mesopic) with a questionnaire. Four wavefront-error representations were computed for a pupil diameter of 6.0 mm and individual physiological pupil diameters at 0.4 lux: (1) the visual Strehl ratio based on optical transfer function (VSOTF), (2) the root-mean-square (RMS) value of Zernike orders 2 to 5 (total RMS), (3) higher-order aberration (HOA) RMS, and (4) a wavefront-error breakdown into the RMS of lower-order aberrations, coma, spherical aberration, and remaining HOA. The impact of the postoperative wavefront error on subjective quality of vision was calculated using linear regression analysis.RESULTS: Fifty-six eyes (29 patients) were included. The ability of wavefront error-derived metrics to predict subjective quality of vision was limited. The VSOTF, calculated for the best-corrected eye, showed the highest predictability. Calculation of wavefront error for individual physiological pupil diameters did not improve predictive ability of the metrics. Eyes with a high theoretical retinal-image quality had a high subjective quality of vision, and eyes with a low subjective quality of vision had a low theoretical image quality.CONCLUSIONS: Postoperative wavefront error had limited influence on the subjective quality of vision. Postoperative retinal image quality should be kept as high as possible to provide good subjective quality of vision.