A comprehensive examination of health conditions associated with obesity in older adults
A comprehensive examination of health conditions associated with obesity in older adults
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DOI：
10.1016/j.amepre.2004.08.001
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发表时间：
2004-12-01
影响因子：
5.5
通讯作者：
White, E
中科院分区：
文献类型：
--
作者：
Patterson, RE;Frank, LL;White, E
背景：美国超过70%的老年人超重或肥胖。为了研究老年人肥胖的总体健康负担，华盛顿州西部的维生素和生活方式队列研究招募了73,003名年龄在50岁到76岁之间的成年人，他们完成了一份关于当前身高和体重、病史和危险因素的自填式问卷。方法：使用2000年至2002年收集的数据进行身体质量指数(BMI)和健康状况的横断面分析。参与者被分为正常体重、超重、肥胖I级或肥胖II/III级。健康状况包括7种严重疾病，2种与心血管疾病风险相关的状况，23种医疗状况，11种健康投诉。Logistic回归模型的优势比(OR)被用来检查四种BMI类别与每种健康状况的关联。结果：在女性中，34%的人超重，16%属于I类肥胖，10%属于II/III类肥胖。在男性中，49%的人超重，18%属于I类肥胖，6%属于II/III类肥胖。总体而言，在为女性检查的41种情况中，37种情况和为男性检查的41种情况中的29种与BMI水平的增加有关(趋势p<；所有模型均为0.05)。对于女性和男性，肥胖II/III与正常体重相比的最高OR分别是糖尿病(OR=12.5和8.3)、膝关节置换(OR=11.7和6.1)和高血压(OR=5.4和5.6)。肥胖还增加了几种罕见疾病的患病几率，如胰腺炎(OR=1.9和1.5)以及慢性疲劳(OR=3.7和3.5)和失眠(OR=3.5和3.1)等健康主诉。临床医生在建议患者减肥时，应该意识到超重或肥胖可能会以各种方式影响患者的健康。(C)2004年《美国预防医学杂志》。
Background: Over 70% of older adults in the United States are overweight or obese. To examine the overall health burden of obesity in older adults, the Vitamins and Lifestyle cohort study of western Washington State recruited 73,003 adults aged 50 to 76 who completed a self-administered questionnaire on current height and weight, medical history, and risk factors.Methods: Cross-sectional analysis of body mass index (BMI) and health conditions was performed using data collected in 2000 to 2002. Participants were categorized as normal weight, overweight, obese I, or obese II/III using BMI cut-points. Health conditions included 7 serious diseases, 2 conditions associated with cardiovascular disease risk, 23 medical conditions, and 11 health complaints. Odds ratios (ORs) from logistic regression models were used to examine associations of the four BMI categories with each health condition. Analyses were gender stratified and adjusted for age, education, race/ethnicity, and smoking status.Results: Among women, 34% were overweight, 16% in the obese I category, and 10% in obese categories II/III. Among men, 49% were overweight, 18% in the obese I category, and 6% in obese categories II/III. Overall, 37 of 41 conditions examined for women and 29 of 41 conditions examined for men were associated with increased levels of BMI (trend p < 0.05 for all models). For women and men, respectively, the highest ORs comparing obese II/III to normal weight were diabetes (OR = 12.5 and 8.3), knee replacement (OR = 11.7 and 6.1), and hypertension (OR = 5.4 and 5.6). Obesity also increased the odds of several rare diseases such as pancreatitis (OR = 1.9 and 1.5) and health complaints such as chronic fatigue (OR = 3.7 and 3.5) and insomnia (OR = 3.5 and 3.1).Conclusions: A broad range of diseases and health complaints are associated with obesity. Clinicians should be aware of the diverse ways in which being overweight or obese may affect the health of their patients when counseling them about weight loss. (C) 2004 American journal of Preventive Medicine.