Cavitation bubble behavior and bubble-shock wave interaction near a gelatin surface as a study of in vivo bubble dynamics
Cavitation bubble behavior and bubble-shock wave interaction near a gelatin surface as a study of in vivo bubble dynamics
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DOI：
10.1007/s003400050022
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发表时间：
2000-01-01
影响因子：
2.1
通讯作者：
Tomita, Y
中科院分区：
文献类型：
--
作者：
Kodama, T;Tomita, Y
研究了明胶表面附近单个空化气泡的破裂，以及附着在明胶表面的气泡与冲击波的相互作用。这些事件使得研究眼内手术、体内和体外冲击波碎石术期间体内空化气泡的行为以及随后的组织损伤机制成为可能。结果是通过高速分幅摄影获得的。明胶表面附近的空化气泡不会产生直接射向表面的明显液体射流，并且倾向于从表面迁移开。对于较宽的相对距离 L/R-max 范围，明胶表面附近空化气泡的运动周期比瑞利塌陷时间的两倍要长，除了非常小的 L/R-max 值（L 是明胶表面与激光焦点位置之间的间隔距离，R-max 是最大气泡半径）。气泡与冲击波的相互作用在气泡内部产生液体射流，渗透到明胶表面。液体射流有可能损坏明胶。结果预测，空化气泡引起的组织损伤与振荡气泡运动、随后的机械组织位移以及剩余气泡与随后的冲击波相互作用产生的液体射流穿透密切相关。特征性的气泡运动和液体射流形成取决于组织的机械性能，导致与在硬质材料上观察到的损伤机制不同。
The collapse of a single cavitation bubble near a gelatin surface, and the interaction of an air bubble attached to a gelatin surface with a shock wave, were investigated. These events permitted the study of the behavior of in vivo cavitation bubbles and the subsequent tissue damage mechanism during intraocular surgery, intracorporeal and extracorporeal shock wave lithotripsy. Results were obtained with high-speed framing photography. The cavitation bubbles near the gelatin surface did not produce significant liquid jets directed at the surface, and tended to migrate away from it. The period of the motion of a cavitation bubble near the gelatin surface was longer than that of twice the Rayleigh's collapse time for a wide range of relative distance, L/R-max, excepting for very small L/R-max values (L was the standoff distance between the gelatin surface and the laser focus position, and R-max was the maximum bubble radius). The interaction of an air bubble with a shock wave yielded a liquid jet inside the bubble, penetrating into the gelatin surface. The liquid jet had the potential to damage the gelatin. The results predicted that cavitation-bubble-induced tissue damage was closely related to the oscillatory bubble motion, the subsequent mechanical tissue displacement, and the liquid jet penetration generated by the interaction of the remaining gas bubbles with subsequent shock waves. The characteristic bubble motion and liquid jet formation depended on the tissue's mechanical properties, resulting in different damage mechanisms from those observed on hard materials.