Femoral osteomyelitis due to Cladophialophora arxii in a patient with chronic granulomatous disease
Femoral osteomyelitis due to Cladophialophora arxii in a patient with chronic granulomatous disease
复制标题
慢性肉芽肿病患者因阿氏刚毛虫引起的股骨骨髓炎
作者：
T. Shigemura;Kazunaga Agematsu;Takashi Yamazaki;Kasuga Eriko;Gaku Yasuda;Kazuko Nishimura;Kenichi Koike
慢性肉芽肿病（CGD）患者的真菌感染是一个预后不良的因素。我们描述了第一例CGD股骨骨髓炎由于Cladophialophora arxii，这是一个成员的dematiaceous组。病原真菌鉴定的基础上，其形态特征，生长温度曲线，和核糖体基因的内部转录空间区域的核苷酸序列。患者通过手术清创成功治疗，随后给予伊曲康唑仑和干扰素-γ。
Fungal infections in patients with chronic granulomatous disease (CGD) are a poor prognostic factor. We describe the first case of CGD with femoral osteomyelitis due to Cladophialophora arxii, which is a member of the dematiaceous group. The causative fungus was identified on the basis of its morphological characteristics, growth temperature profile, and nucleotide sequence on the internal transcribed space region of the ribosomal gene. The patient was successfully treated with surgical debridement, subsequent administration of itraconazolem and interferon-γ.
影响因子：
158.5
作者：
Gallin, JI;Alling, DW;Holland, SM
通讯作者：
Holland, SM