A Case of Pyoderma Gangrenosum on the Stump of an Amputated Right Leg
A Case of Pyoderma Gangrenosum on the Stump of an Amputated Right Leg
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右腿断肢坏疽脓皮病一例
DOI：
10.1111/j.1346-8138.2000.tb02221.x
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发表时间：
2000
期刊：
影响因子：
--
通讯作者：
S. Ishimaru
中科院分区：
文献类型：
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作者：
Y. Umezawa;Shinichi Oyake;T. Oh‐i;T. Nagae;S. Ishimaru
我们在此介绍一例截肢残肢上的坏疽性脓皮病 (PG)。患者是一名69岁的女性，因急性动脉闭塞而双腿截肢。九年后首次出现溃疡，此后溃疡的大小继续波动。并发症包括截肢处局部血流障碍、糖尿病和继发感染。尽管进行了各种治疗，溃疡还是加剧，并证实有低蛋白血症、CRP 升高和发烧。根据患者的临床症状以及溃疡对各种治疗均无反应，该患者被诊断为 PG。给予 40 毫克/天的泼尼松龙后，溃疡显着改善，随后实现了完全上皮化。由于存在多种并发症，确认 PG 极其困难。因此，医生将 PG 视为顽固性溃疡的病因之一非常重要。
We present here a case of pyoderma gangrenosum (PG) on the stump of an amputated leg. The patient was a 69‐year‐old woman who had both of her legs amputated due to acute arterial occlusion. An ulcer first appeared nine years later, after which point it continued to fluctuate in size. Complications included regional blood flow disorder at the amputated stump, diabetes, and secondary infection. Despite various therapies, the ulcer exacerbated, and hypoproteinemia, increased CRP, and fever were confirmed. The patient was diagnosed as having PG based on her clinical symptoms and because the ulcer did not respond to various therapies. The ulcer improved significantly in response to administration of 40 mg/day of prednisolone, and complete epithelialization was later achieved. Given the presence of multiple complications, it was extremely difficult to confirm PG. Therefore, it is important for physicians to consider PG as one of the causes of intractable ulcers.