Chromoselective Photocatalysis: Controlled Bond Activation through Light-Color Regulation of Redox Potentials
Chromoselective Photocatalysis: Controlled Bond Activation through Light-Color Regulation of Redox Potentials
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DOI：
10.1002/anie.201602349
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发表时间：
2016-06-27
影响因子：
16.6
通讯作者：
Koenig, Burkhard
中科院分区：
文献类型：
--
作者：
Ghosh, Indrajit;Koenig, Burkhard
催化剂的活性和选择性可以通过外部刺激来调节，这可能允许复杂分子和药物的有效多步合成。在此，我们报告了光催化剂的氧化还原电位的光色调节，以控制化学键的活化。光催化剂氧化还原能力的光色控制为光氧化还原催化引入了一个新的选择性参数：改变可见光照射的颜色，而不是改变催化剂或配体，从而调节催化转化的选择性。通过使用该原理，通过简单地应用不同颜色的光来激发光催化剂，可以选择性地活化用于C-H芳基化的芳基-卤键和具有不同还原电位的官能团的顺序转化。
Catalysts that can be regulated in terms of activity and selectivity by external stimuli may allow the efficient multistep synthesis of complex molecules and pharmaceuticals. Herein, we report the light-color regulation of the redox potential of a photocatalyst to control the activation of chemical bonds. Light-color control of the redox power of a photocatalyst introduces a new selectivity parameter to photoredox catalysis: Instead of changing the catalyst or ligand, alteration of the color of the visible-light irradiation adjusts the selectivity in catalytic transformations. By using this principle, the selective activation of aryl-halide bonds for C-H arylation and the sequential conversion of functional groups with different reduction potentials is possible by simply applying different colors of light for excitation of the photocatalyst.