The cell biology of acute itch.
The cell biology of acute itch.
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DOI：
10.1083/jcb.201603042
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发表时间：
2016-04-25
期刊：
影响因子：
--
通讯作者：
Dong X
中科院分区：
文献类型：
--
作者：
Green D;Dong X
痒，我们感觉到的刺激和来自抓挠的缓解，是一种进化的警告系统和对有害环境因子的防御。虽然瘙痒曾经被认为是疼痛的一种亚型，但现在被认为是一种独特的感觉，具有自己独特的生理学和细胞受体。在这里，我们讨论了最近的进展，我们的理解痒和分子球员，介导这种感觉方式。
Itch, the irritation we feel and the relief that comes from scratching, is an evolutionary warning system and defense against harmful environmental agents. Although once considered a subtype of pain, itch is now recognized as a unique sense, with its own distinct physiology and cell receptors. Here, we discuss recent advances in our understanding of itch and the molecular players that mediate this sensory modality.