Indocyanine green anterior segment angiography for studying conjunctival vascular changes after trabeculectomy
Indocyanine green anterior segment angiography for studying conjunctival vascular changes after trabeculectomy
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DOI：
10.1046/j.1442-9071.2001.00365.x
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发表时间：
2001-02-01
影响因子：
4
通讯作者：
Aung, T
中科院分区：
文献类型：
--
作者：
Alsagoff, Z;Chew, PTK;Aung, T
背景：本研究的目的是评估使用吲哚菁绿 (ICG) 进行眼前节血管造影，以表征小梁切除术后结膜和巩膜外血管的变化。 方法：这是对首次接受小梁切除术的 10 名患者的 10 只眼睛进行眼前节 ICG 血管造影的前瞻性评估。小梁切除术术中海绵应用5-氟尿嘧啶（5例）或丝裂霉素C（5例）。术前、术后2周和2个月分别进行眼前段ICG血管造影。结果：通过ICG，眼前段血管清晰勾画，包括巩膜深静脉，这是以往血管造影技术无法清晰显示的。还可以研究血管造影的晚期阶段。小梁切除术后的血管改变包括滤泡区域血管分布的丧失以及无血管滤泡周边的血管吻合。结论：使用 ICG 进行血管造影有潜力作为研究小梁切除术后结膜和巩膜外血管系统变化的研究工具。
Background: The aim of the study was to evaluate the use of indocyanine green (ICG) for angiography of the anterior segment to characterize conjunctival and episcleral vasculature changes after trabeculectomy.Methods: This was a prospective evaluation of anterior segment ICG angiography in 10 eyes of 10 patients undergoing trabeculectomy for the first time. Trabeculectomy was performed with intraoperative sponge application of 5- fluorouracil (5 cases) or mitomycin C (5 cases). Anterior segment ICG angiography was performed prior to surgery, then at 2 weeks and 2 months after surgery.Results: With ICG, the anterior segment vessels were well delineated, including deep episcleral veins, which have not been clearly shown in previous angiographic techniques. Late phases of the angiogram could also be studied. The vascular alterations after trabeculectomy noted included loss of vascularity over the bleb area and vascular anastomoses along the perimeter of the avascular bleb.Conclusions: Angiography using ICG has potential as an investigative tool to study the conjunctival and episcleral vasculature changes after trabeculectomy.