A review on the wettability of dental implant surfaces II: Biological and clinical aspects.
A review on the wettability of dental implant surfaces II: Biological and clinical aspects.
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DOI：
10.1016/j.actbio.2014.03.032
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发表时间：
2014-07
影响因子：
9.7
通讯作者：
Boyan BD
中科院分区：
文献类型：
--
作者：
Gittens RA;Scheideler L;Rupp F;Hyzy SL;Geis-Gerstorfer J;Schwartz Z;Boyan BD
牙科和骨科植入物一直在不断发展，以改善其与骨的相互作用，并确保患者的成功结果。表面特征（如表面形貌和表面化学）可用作设计工具，以增强植入物周围的生物反应，体外、体内和临床研究证实了其效果。然而，种植体的综合设计，以促进早期和长期的骨整合，需要更好地了解表面润湿性的作用和它影响周围生物环境的机制。本文综述了实验和市售植入物表面接触角值的可用信息，用于修改植入物表面润湿性的一些技术，以及体外和临床研究的结果。我们的目标是扩大目前的理解，在与血液和生物环境，以及与细菌，硬组织和软组织的界面上的金属植入物的润湿性的作用。
Dental and orthopaedic implants have been under continuous advancement to improve their interactions with bone and ensure a successful outcome for patients. Surface characteristics such as surface topography and surface chemistry can serve as design tools to enhance the biological response around the implant, with in vitro, in vivo and clinical studies confirming their effects. However, the comprehensive design of implants to promote early and long-term osseointegration requires a better understanding of the role of surface wettability and the mechanisms by which it affects the surrounding biological environment. This review provides a general overview of the available information about the contact angle values of experimental and of marketed implant surfaces, some of the techniques used to modify surface wettability of implants, and results from in vitro and clinical studies. We aim to expand the current understanding on the role of wettability of metallic implants at their interface with blood and the biological milieu, as well as with bacteria, and hard and soft tissues.