Prognostic Value of 18F-Fluorodeoxyglucose Positron Emission Tomography in Patients with Resectable Pancreatic Cancer
Prognostic Value of 18F-Fluorodeoxyglucose Positron Emission Tomography in Patients with Resectable Pancreatic Cancer
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DOI：
10.3349/ymj.2013.54.6.1377
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发表时间：
2013-11-01
影响因子：
2.4
通讯作者：
Lee, Jae-Hoon
中科院分区：
文献类型：
--
作者：
Choi, Hye Jin;Kang, Chang Moo;Lee, Jae-Hoon
目的：我们评估了F-18-2-氟-2-脱氧葡萄糖正电子发射断层扫描（FDG PET）在可切除胰腺癌患者中的预后价值。材料与方法：我们回顾性分析了接受根治性切除术的胰腺癌患者的病历，其中包括64例术前进行FDG PET扫描的连续患者。测量原发性胰腺癌的最大标准化摄取值（SUVmax）进行统计学分析。通过Kaplan-Meier方法估计生存时间，并使用考克斯比例风险模型来确定SUVmax是否增加了关于生存的新预测信息以及已知的预后因素。p3.5）显示OS和DFS显著短于低SUVmax组。多因素分析显示，SUVmax高、肿瘤分化差是影响预后的独立危险因素。结论：我们的研究表明，FDG摄取程度是胰腺癌根治性切除患者的独立预后因素。
Purpose: We evaluated the prognostic value of F-18-2-fluoro-2-deoxyglucose positron emission tomography (FDG PET) in patients with resectable pancreatic cancer. Materials and Methods: We retrospectively reviewed the medical records of pancreatic cancer patients who underwent curative resection, which included 64 consecutive patients who had preoperative FDG PET scans. For statistical analysis, the maximal standardized uptake value (SUVmax) of primary pancreatic cancer was measured. Survival time was estimated by the Kaplan-Meier method, and Cox's proportional hazard model was used to determine whether SUVmax added new predictive information concerning survival together with known prognostic factors. p3.5) showed significantly shorter OS and DFS than the low SUVmax group. Multivariate analysis of OS and DFS showed that both high SUVmax and poor tumor differentiation Were independent poor prognostic factors. Conclusion: Our study showed that degree of FDG uptake was an independent prognostic factor in pancreatic cancer patients who underwent curative resection.