Conservation of eukaryotic sterol homeostasis: new insights from studies in budding yeast.
Conservation of eukaryotic sterol homeostasis: new insights from studies in budding yeast.
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DOI：
10.1016/s1388-1981(00)00145-1
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发表时间：
2000-12
期刊：
影响因子：
--
通讯作者：
S. Sturley
中科院分区：
文献类型：
--
作者：
S. Sturley
The model eukaryote Saccharomyces cerevisiae (budding yeast) has provided significant insight into sterol homeostasis. The study of sterol metabolism in a genetically amenable model organism such as yeast is likely to have an even greater impact and relevance to human disease with the advent of the complete human genome sequence. In addition to definition of the sterol biosynthetic pathway, almost to completion, the remarkable conservation of other components of sterol homeostasis are described in this review.
