Four Drosophila heat shock genes at 67B: characterization of recombinant plasmids.
Four Drosophila heat shock genes at 67B: characterization of recombinant plasmids.
复制标题
67B 的四个果蝇热休克基因：重组质粒的表征。
DOI：
10.1093/nar/8.19.4441
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发表时间：
1980
影响因子：
14.9
通讯作者：
B. Mccarthy
中科院分区：
文献类型：
--
作者：
E. Craig;B. Mccarthy
已分离出黑腹果蝇基因组67 B位点的一个33位酶区域。27 K、26 K、23 K和22 K热激诱导蛋白的基因包含在11 kb片段内。约1.4kb长的27 K基因和约1.0kb长的23 K基因被约1.5kb的间隔DNA隔开;编码26 K基因的第三转录块约1.1kb长，并与23 K蛋白质的基因被4.5kb的间隔DNA隔开。22 K基因位于距离26 K基因约1.2kb处。编码27 K、23 K和22 K基因的RNA从相同的DNA链转录。随着四个小的热休克诱导蛋白的分配到67 B，所有七个主要的热休克诱导蛋白的基因还没有被定位细胞学。
A 33 kilobase region of the 67B locus of Drosophila melanogaster genome has been isolated. The genes for the 27K, 26K, 23K and 22K heat shock induced proteins are contained within an 11 kb segment. the 27K gene, approximately 1.4 kb in length, and the 23K gene, approximately 1.0 kb in length, are separated by about 1.5 kb of spacer DNA; a third block of transcription, which encodes the 26K gene, is approximately 1.1 kb in length, and is separated from the gene for the 23K protein by 4.5 kb of spacer DNA. The 22K gene is located approximately 1.2 kb from the 26K gene. The RNAs encoding the 27K, 23K and 22K genes are transcribed from the same DNA strand. With the assignment of the four small heat shock induced proteins to 67B, genes for all seven major heat shock induced proteins have no been mapped cytologically.