What is Elective Oncologic Surgery in the Time of COVID-19? A Literature Review of the Impact of Surgical Delays on Outcomes in Patients with Cancer.
What is Elective Oncologic Surgery in the Time of COVID-19? A Literature Review of the Impact of Surgical Delays on Outcomes in Patients with Cancer.
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DOI：
10.31487/j.cor.2020.06.05
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发表时间：
2020-06
期刊：
影响因子：
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通讯作者：
DeMore NK
中科院分区：
文献类型：
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作者：
Garcia D;Siegel JB;Mahvi DA;Zhang B;Mahvi DM;Camp ER;Graybill W;Savage SJ;Giordano A;Giordano S;Carneiro-Pla D;Javid M;Lesher AP;Abbott A;DeMore NK
COVID-19 大流行的影响已超出了 SARS-CoV-2 感染者的范围。它的广泛后果影响了癌症患者，他们的手术可能会被推迟，以尽量减少暴露并节省资源。每个肿瘤外科亚专业的专家都被选来对相关文献进行审查。文章是通过 PubMed 搜索每种癌症亚型使用以下术语获得的：手术延迟、手术时间、结果和生存。乳腺癌、导管原位癌、T1 胰腺癌、卵巢癌和小儿骨肉瘤的手术延迟 > 4 周会对生存产生负面影响。对肝细胞癌、结肠癌和黑色素瘤（第一期）的研究表明，生存率降低且延迟 > 3 个月。研究表明，短期手术延误可能会对多种癌症类型以及原位癌的患者预后产生负面影响。相反，其他癌症，如胃癌、晚期黑色素瘤和胰腺癌、分化良好的甲状腺癌和几种泌尿生殖系统癌症，与手术延迟没有显着的结果差异。
The impact of the COVID-19 pandemic has spread beyond those infected with SARS-CoV-2. Its widespread consequences have affected cancer patients whose surgeries may be delayed in order to minimize exposure and conserve resources. Experts in each surgical oncology subspecialty were selected to perform a review of the relevant literature. Articles were obtained through PubMed searches in each cancer subtype using the following terms: delay to surgery, time to surgery, outcomes, and survival. Delays in surgery > 4 weeks in breast cancer, ductal carcinoma in situ, T1 pancreatic cancer, ovarian cancer, and pediatric osteosarcoma, negatively impacted survival. Studies on hepatocellular cancer, colon cancer, and melanoma (Stage I) demonstrated reduced survival with delays > 3 months. Studies have shown that short-term surgical delays can result in negative impacts on patient outcomes in multiple cancer types as well as in situ carcinoma. Conversely, other cancers such as gastric cancer, advanced melanoma and pancreatic cancer, well-differentiated thyroid cancer, and several genitourinary cancers demonstrated no significant outcome differences with surgical delays.