PF1018, A NOVEL INSECTICIDAL COMPOUND PRODUCED BY HUMICOLA SP
PF1018, A NOVEL INSECTICIDAL COMPOUND PRODUCED BY HUMICOLA SP
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DOI：
10.7164/antibiotics.47.571
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发表时间：
1994-05-01
影响因子：
3.3
通讯作者：
KOYAMA, M
中科院分区：
文献类型：
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作者：
GOMI, S;IMAMURA, K;KOYAMA, M
从腐霉发酵液中分离得到一种新的杀虫化合物PF1018。它对多种关键害虫表现出杀虫活性。核磁共振光谱分析结合X-射线晶体分析和化学降解研究确定其结构为(7aS)-2-((2E)-1-hydroxy-3-((1S，3aR，4R，5R，7aR)-3a，4，5，7a-tetrahydro-1，3，5，7-tetramethyl-5，1-((3S)-(Z)-2，3-dimethylpropeno)-1H-inden-4-yl)-2-propenylidene)pyrrolizidine-1，3-dione，。
A new insecticidal compound PF1018 was isolated from the culture broth of Humicola sp. It exhibited insecticidal activity against a wide range of critical pest species. The structure of PF1018 was determined to be (7aS)-2-((2E)-1-hydroxy-3-((1S,3aR,4R,5R,7aR)-3a,4,5,7a-tetrahydro-1,3,5,7-tetramethyl-5,1-((3S)-(Z)-2,3-dimethylpropeno)-1H-inden-4-yl)-2-propenylidene)pyrrolizidine-1,3-dione, by NMR spectral analyses coupled with X-ray crystallographic analysis and chemical degradation study.