High-resolution T1 and T2 mapping of the brain in a clinically acceptable time with DESPOT1 and DESPOT2
High-resolution T1 and T2 mapping of the brain in a clinically acceptable time with DESPOT1 and DESPOT2
复制标题
DOI：
10.1002/mrm.20314
复制
发表时间：
2005-01-01
影响因子：
3.3
通讯作者：
Rutt, BK
中科院分区：
文献类型：
--
作者：
Deoni, SCL;Peters, TM;Rutt, BK
固有T - 1和T - 2弛豫时间的变化与许多神经系统疾病有关。不幸的是，传统方法相关的低分辨率和长成像时间阻碍了T - 1和T - 2成像成为常规临床评估的一部分。在这项研究中，对DESPOT1和DESPOT2成像方法用于高分辨率、全脑T - 1和T - 2成像的临床适用性进行了研究。在体内，以1.5T的磁场强度获取了6名健康志愿者的1立方毫米各向同性全脑T - 1和T - 2图像，成像时间为……
Variations in the intrinsic T-1 and T-2 relaxation times have been implicated in numerous neurologic conditions. Unfortunately, the low resolution and long imaging time associated with conventional methods have prevented T-1 and T-2 mapping from becoming part of routine clinical evaluation. In this study, the clinical applicability of the DESPOT1 and DESPOT2 imaging methods for high-resolution, whole-brain, T-1 and T-2 mapping was investigated. In vivo, 1-mm(3) isotropic whole-brain T-1 and T-2 maps of six healthy volunteers were acquired at 1.5 T with an imaging time of