Study on X-ray enhancement in Laser-Compton scattering for auger therapy

Study on X-ray enhancement in Laser-Compton scattering for auger therapy
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DOI:
10.1080/09553002.2020.1811420
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发表时间:
2020-08
影响因子:
2.6
通讯作者:
Y. Koshiba;R. Morita;Koki Yamashita;M. Washio;K. Sakaue;T. Higashiguchi;J. Urakawa
Y. Koshiba;R. Morita;Koki Yamashita;M. Washio;K. Sakaue;T. Higashiguchi;J. Urakawa
中科院分区:
医学3区
文献类型:
--
作者:
Y. Koshiba;R. Morita;Koki Yamashita;M. Washio;K. Sakaue;T. Higashiguchi;J. Urakawa

文献摘要

相似文献

摘要目的高亮度单色硬X射线在包括俄歇治疗在内的医疗应用中具有重要的应用价值。人们可以通过激光-康普顿散射(LCS)产生这样的X射线,方法是允许来自紧凑型激光系统的光子与由紧凑型电子加速器加速的电子相互作用。本文在简要介绍了激光-康普顿X射线源的基础上,提出了一种提高激光-康普顿X射线强度的方案--螃蟹交叉方案。评价了螃蟹杂交的效果,并报道了我们研制的用于螃蟹杂交LCS研究的专用激光系统。材料与方法对螃蟹杂交后的光度增强因子进行了评价。对于电子束,将使用射频偏转器来产生倾斜的电子束。激光系统采用啁啾脉冲放大。激光增益介质采用掺Yb光纤和Yb:YAG薄片。结果当交叉角为45度时,螃蟹交叉处的光度增强因子为3.8。利用薄片再生放大器获得了10mJ的脉冲能量。脉冲压缩后的脉冲宽度约为1.5ps。结论我们将演示电子束和激光脉冲的交叉增强LCS X射线。预期增强系数为3.8。我们已经成功地完成了激光器的研制,不久将进行原理验证实验。
Abstract Purpose Monochromatic hard X-rays with high brightness are desired for medical applications including Auger therapy. One can generate such X-rays through laser-Compton scattering (LCS) by allowing photons from a compact laser system to interact with electrons accelerated by a compact electron accelerator. In this paper, after a brief description of laser-Compton X-ray sources, a scheme called crab crossing to enhance the X-ray intensity is proposed. The effect of crab crossing is evaluated, and we report our dedicated laser system for the crab crossing LCS research. Materials and methods The luminosity enhancement factor by crab crossing is evaluated. For the electron beam, a rf deflector will be used to generate a tilted electron beam. For the laser system, chirped pulsed amplification is adopted. Yb-doped optical fibers and a Yb:YAG thin-disk is used for the laser gain media. Results The luminosity enhancement factor by crab crossing is expected to be 3.8 when the crossing angle is 45 degrees. 10mJ pulse energy was achieved by thin-disk regenerative amplifier. The pulse duration after the pulse compressor was about 1.5 ps. Conclusion We are going to demonstrate the LCS X-ray enhancement by crab crossing of electron beam and laser pulse. The expected enhancement factor is 3.8. We have successfully finished the laser development and the proof-of-principle experiment will be conducted soon.