NOD2 gene variants are a risk factor for culture-positive spontaneous bacterial peritonitis and monomicrobial bacterascites in cirrhosis

NOD2 gene variants are a risk factor for culture-positive spontaneous bacterial peritonitis and monomicrobial bacterascites in cirrhosis
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DOI:
10.1111/j.1478-3231.2011.02561.x
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发表时间:
2012-02-01
影响因子:
6.7
通讯作者:
Stallmach, Andreas
Stallmach, Andreas
中科院分区:
医学2区
文献类型:
--
作者:
Bruns, Tony;Peter, Jack;Stallmach, Andreas

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背景:自发性细菌性腹膜炎(SBP)被认为是细菌从胃肠道腔转移到肠系膜淋巴结并随后循环的结果。在最近的一项研究中,NOD2基因的变异有助于细菌易位并与收缩压相关。
Background: Spontaneous bacterial peritonitis (SBP) is considered as result of bacterial translocation from the gastrointestinal lumen to the mesenteric lymph nodes and subsequent circulation. Variants of the NOD2 gene contribute to bacterial translocation and were associated with SBP in a recent study.