Manifestation of scotomas created by transcranial magnetic stimulation of human visual cortex
Manifestation of scotomas created by transcranial magnetic stimulation of human visual cortex
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DOI：
10.1038/11245
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发表时间：
1999-08-01
影响因子：
25
通讯作者：
Shimojo, S
中科院分区：
文献类型：
--
作者：
Kamitani, Y;Shimojo, S
在经颅磁刺激(TMS)下，人类视觉皮质的视觉表现下降表明其空间范围不直接可见的抑制。我们创建了一个人工暗点(视觉模式中缺失的区域)，通过使用磁脉冲跟随大视野、图案化的视觉刺激，直接可视化TMS诱导的抑制的位置、大小和形状。根据已知的视皮层地形图，暗点随着线圈的位置而移位。视觉抑制导致图形依赖的失真，暗点被时间上相邻的刺激填满，暗示了空间和时间的完成机制。因此，对TMS诱导的抑制的知觉测量可能通过神经元连接和神经信号的时间相互作用提供关于皮质处理的信息。
Reduced visual performance under transcranial magnetic stimulation (TMS) of human visual cortex demonstrates suppression whose spatial extent is not directly visible. We created an artificial scotoma (region missing from a visual pattern) to directly visualize the location, size and shape of the TMS-induced suppression by following a large-field, patterned, visual stimulus with a magnetic pulse. The scotoma shifted with coil position according to known topography of visual cortex. Visual suppression resulted in pattern-dependent distortion, and the scotoma was filled in with temporally adjacent stimuli, suggesting spatial and temporal completion mechanisms. Thus, perceptual measurements of TMS-induced suppression may provide information about cortical processing via neuronal connections and temporal interactions of neural signals.