Toxigenic bacteria and sudden infant death syndrome (SIDS): nasopharyngeal flora during the first year of life
Toxigenic bacteria and sudden infant death syndrome (SIDS): nasopharyngeal flora during the first year of life
复制标题
DOI：
10.1111/j.1574-695x.1999.tb01326.x
复制
发表时间：
1999-08-01
影响因子：
--
通讯作者：
Busuttil, A
中科院分区：
文献类型：
--
作者：
Blackwell, CC;MacKenzie, DAC;Busuttil, A
婴儿猝死综合征（SIDS）的许多发育和环境危险因素与呼吸道感染的易感性相似，并且在一些SIDS病例中涉及致炎细菌。我们评估了健康婴儿鼻咽部植物群与危险因素的关系，以确定哪些物种最适合为常见细菌毒素假说提出的数学模型，以及这些发现是否补充了调查期间发生的SIDS病例的结果。1993年4月至1996年3月对253名健康婴儿及其母亲进行了纵向研究，其中150名来自多贫困地区，103名来自富裕地区。并发SIDS婴儿（37例）接受鼻咽诺拉筛查。在小于或等于3个月的健康婴儿中，主要分离株为金黄色葡萄球菌，占57%，而在该年龄段的SIDS婴儿中为86%（P
Many developmental and environmental risk factors for sudden infant death syndrome (SIDS) are similar to those for susceptibility to respiratory tract infection, and toxigenic bacteria have been implicated in some SIDS cases. We assessed nasopharyngeal flora of healthy infants in relation to risk factors to determine which species best fit the mathematical model proposed for the common bacterial toxin hypothesis and if these findings complemented results obtained from SIDS cases which occurred during the period of the survey. Longitudinal studies were carried out between April 1993 and March 1996 on 253 healthy infants and their mothers, 150 from a multiply deprived area, 103 from an affluent area. Concurrent SIDS infants (37) were screened for nasopharyngeal nora. Among healthy infants less than or equal to 3 months of age, the predominant isolate was Staphylococcus aureus, 57% compared with 86% for SIDS infants in that age range (P