Processing of olfactory information at three neuronal levels in the spiny lobster
Processing of olfactory information at three neuronal levels in the spiny lobster
复制标题
大龙虾三个神经元水平的嗅觉信息处理
DOI：
10.1016/0006-8993(84)90841-2
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发表时间：
1984
期刊：
影响因子：
2.9
通讯作者：
B. Ache
中科院分区：
文献类型：
--
作者：
C. Derby;K. Hamilton;B. Ache
在龙虾嗅觉系统中，从受体细胞和化学感觉中间神经元三个水平对气味质量编码进行了分析。在每个水平上记录对这种动物最具刺激性的三种化合物-牛磺酸、谷氨酸和甜菜碱的反应，以比较基本的神经元反应特性、单细胞和群体反应光谱以及跨神经元模式。在每个连续的神经元水平上，细胞的平均反应特异性增加。受体细胞和低阶中间神经元之间调谐宽度的增加与神经元间刺激间相关性的增加是平行的。然而，在高阶中间神经元中，跨神经元的相关性相对下降，这表明较宽调谐的高阶中间神经元比较窄调谐的低阶中间神经元更能区分任何两种化合物。虽然刺激质量似乎是由中间神经元以跨纤维模式编码的，但一些低阶和高阶中间神经元保留了受体细胞的狭义特异性这一事实表明，标记线可能在龙虾整个嗅觉通路的编码中起着重要作用。
Odor quality coding was analyzed at three neuronal levels, receptor cell and two levels of chemosensory interneurons, in the olfactory system of the spiny lobsterPanulirus argus. Responses to three of the most stimulatory compounds for this animal—taurine, glutamate and betaine—were recorded at each level in order to compare basic neuronal response properties, single cell and population response spectra, and across-neuron patterns. Mean response specificity increased for cells at each successive neuronal level. The increase in breadth of tuning between receptor cells and low-order interneurons was paralleled by an increase in interstimulus across-neuron correlations. However, in high-order interneuronns, there was relative decline in across-neuron correlations, indicating that the more broadly-tuned high-order interneurons are better able to discriminate between any two compounds than are the more narrowly-tuned low-order interneurons. Although stimulus quality appears to be coded by interneurons as an across-fiber pattern, the fact that some low-order and high-order interneurons retained the narrow specificity of receptor cells suggests that labeled lines may have an important funtion in coding throughout the olfactory pathway of thespiny lobster.