Statistical modelling of data showing pandemic H1N1 2009 swine influenza a virus infection kinetics in vaccinated pigs.
Statistical modelling of data showing pandemic H1N1 2009 swine influenza a virus infection kinetics in vaccinated pigs.
复制标题
显示 2009 年 H1N1 甲型流感病毒在已接种疫苗的猪中的感染动力学的数据统计模型。
DOI：
10.1016/j.dib.2019.104576
复制
发表时间：
2019
期刊：
影响因子：
1.2
通讯作者：
Canini L
中科院分区：
文献类型：
--
作者：
Canini L
采用猪流感大流行2009年H1N1 （pH1N1）病毒在猪攻毒模型中研究与该病毒同源或异源全灭活疫苗以及商业疫苗的效力。每日通过实时定量RT-PCR （RRT-qPCR）监测病毒RNA的鼻腔脱落情况，详见(1)。在这里，我们报告了病毒RNA脱落动力学的统计建模。
A swine influenza A pandemic 2009 H1N1 (pH1N1) virus was used in a pig challenge model to investigate the efficacy of whole inactivated vaccines homologous or heterologous to the challenge virus as well as a commercial vaccine. Nasal shedding of viral RNA was monitored daily by real-time, quantitative RT-PCR (RRT-qPCR) as detailed (1). Here we report the statistical modelling of the viral RNA shedding kinetics.