Prevalence and risk factors for nasopharyngeal carriage of Streptococcus pneumoniae among adolescents
Prevalence and risk factors for nasopharyngeal carriage of Streptococcus pneumoniae among adolescents
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DOI：
10.1099/jmm.0.47470-0
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发表时间：
2008-02-01
影响因子：
3
通讯作者：
Brandileone, Maria-Cristina C.
中科院分区：
文献类型：
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作者：
Cardozo, Dea M.;Nascimento-Carvalho, Cristiana M.;Brandileone, Maria-Cristina C.
关于青少年中鼻咽部肺炎的患病率及其危险因素的数据很少。本研究的目的就是提供这种信息。进行了一项横断面、基于人群的前瞻性研究。参与者是10 - 13青少年（年龄范围10 - 19岁）随机招募在22所公立学校。这些学校是从巴西萨尔瓦多11个卫生区的307所公立学校中随机选出的。通过标准程序评估鼻咽样品以回收和鉴定肺炎链球菌。通过基于标准化问卷的保密访谈收集潜在危险因素的数据。肺炎球菌从8.2%[83/1013，95%置信区间（CI）6.6 - 10.0]恢复。通过逐步logistic回归分析，肺炎球菌定植与年轻年龄独立相关[比值比（OR）0.85，95%CI 0.77 - 0.94，P = 0.001]，男性（OR 1.78，95%CI 1.11 - 2.85，P = 0.02），家庭被动吸烟暴露（OR 1.76，95%CI 1.10 - 2.79，P = 0.02），招募期间有上呼吸道感染（OR 2.67，95%CI 1.67 - 4.28，P
Data on the prevalence of pneumooccal nasopharyngeal carriage and its risk factors among adolescents are scarce. The aim of this study was to provide such information. A cross-sectional, population-based prospective study was conducted. Participants were 10 13 adolescents (age range 10-19 years) randomly recruited in 22 public schools. Those schools were randomly chosen among 307 public schools from 11 Sanitary Districts of Salvador, Brazil. Nasopharyngeal samples were assessed by standard procedures to recover and identify Streptococcus pneumoniae. Data on potential risk factors were gathered by confidential interview based on a standardized questionnaire. Pneumococci were recovered from 8.2% [83/1013, 95% confidence interval (CI) 6.6-10.0]. By stepwise logistic regression, pneumococcal colonization was independently associated with younger age [odds ratio (OR) 0.85, 95% Cl 0.77-0.94, P=0.001], being male (OR 1.78, 95% CI 1.11-2.85, P=0.02), exposure to passive smoke in the household (OR 1.76, 95% CI 1.10-2.79, P=0.02), having an upper respiratory infection during recruitment (OR 2.67, 95% CI 1.67-4.28, P