Agreement between self-reported smoking and cotinine concentration in adolescents:: A validation study in Brazil
Agreement between self-reported smoking and cotinine concentration in adolescents:: A validation study in Brazil
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DOI：
10.1016/j.jadohealth.2008.02.002
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发表时间：
2008-09-01
影响因子：
7.6
通讯作者：
Hallal, Pedro C.
中科院分区：
文献类型：
--
作者：
Malcon, Maura C.;Menezes, Ana M. B.;Hallal, Pedro C.
目的：为了验证自我报告的数据在青少年吸烟与可替宁concentration.Methods比较：2009第七和第八年级的学生从32所公立学校在巴西佩尔蒂尼奥。在教育干预之前和之后，青少年被联系两次，并采集尿液样本进行可替宁分析。在本文中，只提供了基线阶段的数据。高效液相色谱法用于可替宁分析。使用了可替宁的两个临界点：10 ng/mL和30 ng/mL。两个自我报告的吸烟变量：在过去的30天内至少有一支香烟吸烟;和每日smoking.Results：在过去的30天内吸烟的自我报告的患病率为7.4%，和0.9%的青少年报告为每日吸烟者。那些在过去30天内报告吸烟的人的平均可替宁值比那些报告不吸烟的人高10倍。使用可替宁10 ng/mL的临界值，自我报告吸烟的灵敏度为16.3%（95%置信区间[CI] 11.7：20.9），特异性为93.6%（95% CI 92.8; 95.0）。使用30 ng/mL的截止值，灵敏度为22.6%（95%CI 15.6; 29.6），特异性为93.7%（95%CI 92.6; 94.8）。结论：自我报告的吸烟与可替宁浓度的一致性较低，表明青少年低估了烟草消费。(c)2008青少年医学会。All rights reserved.
Purpose: To validate self-reported data on smoking in adolescents in comparison with cotinine concentration.Methods: Two thousand two hundred nine seventh- and eighth-grade students from 32 public schools in Pelotas, Brazil. Adolescents were contacted twice-before and after an educational intervention-and samples Of urine for cotinine analyses were taken. In this paper, only data from the baseline phase are presented. High-performance liquid chromatography was used for cotinine analysis. Two cutoff points for cotinine were used: 10 ng/mL and 30 ng/mL. Two self-reported smoking variables were used: at least one cigarette smoked in the previous 30 days; and daily smoking.Results: The self-reported prevalence of smoking in the previous 30 days was 7.4%, and 0.9% of the adolescents reported to be daily smokers. Those who reported smoking in the previous 30 days presented mean cotinine values 10 times greater than those who reported to be nonsmokers. Using a cutoff of 10 ng/mL for cotinine, sensitivity of self-reported smoking was 16.3% (95% confidence interval [CI] 11.7: 20.9) and specificity was 93.6% (95% CI 92.8; 95.0). Using a cutoff of 30 ng/mL, sensitivity was 22.6% (95% CI 15.6; 29.6) and specificity was 93.7% (95% CI 92.6; 94.8).Conclusions: Self-reported smoking presents low agreement with cotinine concentration, suggesting that adolescents underestimate tobacco consumption. (c) 2008 Society for Adolescent Medicine. All rights reserved.