Surgical Resection for Esophageal Cancer Synchronously or Metachronously Associated with Head and Neck Cancer
Surgical Resection for Esophageal Cancer Synchronously or Metachronously Associated with Head and Neck Cancer
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DOI：
10.1245/s10434-013-2875-z
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发表时间：
2013-07-01
影响因子：
3.7
通讯作者：
Maehara, Yoshihiko
中科院分区：
文献类型：
--
作者：
Morita, Masaru;Kawano, Hiroyuki;Maehara, Yoshihiko
食道癌常与头颈部癌症有关，在这种情况下，食道切除术通常很困难。为探讨食管癌合并头颈部癌行食管癌切除术的临床意义，对26例头颈部癌患者行食管癌切除术的临床疗效进行了比较（双癌组）和176例无头颈癌双癌组5例分期手术，3例加吻合微血管，4例加肌瓣。双癌组的死亡率和发病率分别为0和35%，与对照组（分别为3%和31%）无显著差异。双癌组和对照组的总生存率无显著差异，5年生存率分别为59%和49%.Esophageal切除术是一种有效的治疗方法，如果采用适合每个病例的技术，如分期手术，肌皮瓣，微血管吻合，即使是在食管和头颈部双癌患者。
Esophageal cancer is frequently associated with head and neck cancer, and esophagectomy is usually difficult in such a case. The purpose of this study was to clarify the clinical significance of esophagectomy for patients with esophageal cancer associated either synchronously or metachronously with head and neck cancer.The clinical outcomes of surgical resections for esophageal cancer were compared between 26 patients with head and neck cancer (double cancer group) and 176 without head and neck cancer (control group).Staged operations were performed in 5 patients in the double cancer group, while microvascular anastomosis as well as a muscle flap was added for 3 and 4 patients, respectively. The mortality and morbidity of the double cancer group were 0 and 35 %, respectively, which were not significantly different from those of the control group (3 and 31 %, respectively). There were no significant differences in overall survival in the double cancer and control groups, which had 5-year survival rates of 59 and 49 %, respectively.Esophagectomy can be an effective treatment when techniques are adopted that are appropriate for each case, such as staged operations, muscular flaps, and microvascular anastomosis, even in patients with double cancers of the esophagus and the head and neck.