Medication Adherence Measures: An Overview.
Medication Adherence Measures: An Overview.
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DOI：
10.1155/2015/217047
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发表时间：
2015
影响因子：
--
通讯作者：
Fresco P
中科院分区：
文献类型：
--
作者：
Lam WY;Fresco P
世卫组织报告说，在发达国家，慢性病患者的依从性平均只有50%。这被认为是一个重大的公共卫生问题，因为不遵守药物治疗会导致不良的健康结果和增加的医疗保健费用。因此，改善药物依从性是至关重要的，许多研究表明，干预措施可以改善药物依从性。提高药物依从性策略的一个重要方面是了解其重要性。然而，研究人员和医疗保健专业人员缺乏一般指导，以选择适当的工具来探索药物依从性的程度和这个问题背后的原因，以便协调后续的干预措施。本文综述了主观和客观的药物依从性测量，包括直接测量，涉及二次数据库分析，电子药物包装（EMP）设备，药片计数，临床医生评估和自我报告。主观测量通常为患者的不依从性提供解释，而客观测量有助于更准确地记录患者的服药行为。在选择合适的方法时，研究人员和医疗保健专业人员应该平衡可靠性和实用性，特别是成本效益。同时，由于不存在完美的测量方法，因此多测量方法似乎是目前的最佳解决方案。
WHO reported that adherence among patients with chronic diseases averages only 50% in developed countries. This is recognized as a significant public health issue, since medication nonadherence leads to poor health outcomes and increased healthcare costs. Improving medication adherence is, therefore, crucial and revealed on many studies, suggesting interventions can improve medication adherence. One significant aspect of the strategies to improve medication adherence is to understand its magnitude. However, there is a lack of general guidance for researchers and healthcare professionals to choose the appropriate tools that can explore the extent of medication adherence and the reasons behind this problem in order to orchestrate subsequent interventions. This paper reviews both subjective and objective medication adherence measures, including direct measures, those involving secondary database analysis, electronic medication packaging (EMP) devices, pill count, and clinician assessments and self-report. Subjective measures generally provide explanations for patient's nonadherence whereas objective measures contribute to a more precise record of patient's medication-taking behavior. While choosing a suitable approach, researchers and healthcare professionals should balance the reliability and practicality, especially cost effectiveness, for their purpose. Meanwhile, because a perfect measure does not exist, a multimeasure approach seems to be the best solution currently.