Central mucoepidermoid carcinoma of the mandible: report of four cases with long-term follow-up
Central mucoepidermoid carcinoma of the mandible: report of four cases with long-term follow-up
复制标题
DOI：
10.1054/ijom.2002.0374
复制
发表时间：
2003-08-01
影响因子：
2.4
通讯作者：
Kowalski, LP
中科院分区：
文献类型：
--
作者：
Pires, FR;de Almeida, OP;Kowalski, LP
中心性粘液表皮样癌是一种罕见的肿瘤，约占所有粘液表皮样癌的2%至4%。它们是组织学上级别较低的癌症，通常以单房性或多房性放射学病变形式影响下颌骨。作者报告了四例影响下颌骨的中央性粘液表皮样癌，并讨论了他们的临床、放射学和组织学表现。4名女性受累，平均年龄42岁，所有病例均累及下颌后部。治疗包括3例手术和1例颈淋巴清扫术和放射治疗。两名患者在平均78个月的随访中没有复发，并且活着，没有疾病的迹象。另2例患者局部复发，1例随访384个月后带病存活，另1例随访324个月死于其他原因，无肿瘤征象。下颌骨中心性粘液表皮样癌是一种低级别肿瘤，有效的手术治疗包括广泛的局部切除或整块切除，使患者在长期随访后有良好的预后。
Central mucoepidermoid carcinomas are uncommon tumours, representing about 2 to 4% of all mucoepidermoid carcinomas. They are histologically low-grade cancers, usually affecting the mandible as uni- or multilocular radiographic lesions. The authors report four cases of central mucoepidermoid carcinomas affecting the mandible and discuss their clinical, radiographic and histological findings. Four females were affected, with a mean age of 42 years and all cases involved the posterior mandible. Treatment included surgery in three cases and surgery associated to neck dissection and radiotherapy in one case. Two patients showed no recurrence and were alive without signs of the disease after a mean follow-up of 78 months. The other two patients showed local recurrence and one was alive with disease after a follow-up of 384 months, and the other was followed-up for 324 months dying by other causes without signs of the tumour. Central mucoepidermoid carcinomas of the mandible are low-grade tumours, and effective surgical treatment involving wide local excision or en bloc resection allows patients to have a favourable prognosis after long-term follow-up.