Deformable Slice-to-Volume Registration for Motion Correction of Fetal Body and Placenta MRI

Deformable Slice-to-Volume Registration for Motion Correction of Fetal Body and Placenta MRI
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DOI:
10.1109/tmi.2020.2974844
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发表时间:
2020-09-01
影响因子:
10.6
通讯作者:
Deprez, Maria
Deprez, Maria
中科院分区:
工程技术1区
文献类型:
--
作者:
Uus, Alena;Zhang, Tong;Deprez, Maria

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在子宫内MRI中,由于存在由弯曲和拉伸引起的器官的局部非刚性变换,胎儿身体和胎盘的运动校正构成了特别的挑战。现有的切片到体积配准(SVR)重建方法被广泛用于仅经历刚性变换的胎儿大脑的运动校正。然而,对于胎儿身体和胎盘的重建,刚性配准不能解决由于可变形运动引起的配准错误的问题,导致重建体积中的特征退化。我们提出了一种可变形的支持向量回归机(DSVR),一种新的方法,用于非刚性运动校正的胎儿MRI的基础上分层可变形的支持向量回归机计划,以允许高分辨率重建胎儿的身体和胎盘。此外,基于结构的离群值拒绝的鲁棒方案最大限度地减少了配准误差的影响。DSVR的改进性能相比,SVR和补丁体积注册(PVR)的方法定量证明了在模拟实验和20个胎儿MRI数据集从28-31周胎龄(GA)的范围内不同程度的运动腐败。此外,我们提出了定性评价100例胎儿体从20-34周GA范围。
In in-utero MRI, motion correction for fetal body and placenta poses a particular challenge due to the presence of local non-rigid transformations of organs caused by bending and stretching. The existing slice-to-volume registration (SVR) reconstruction methods are widely employed for motion correction of fetal brain that undergoes only rigid transformation. However, for reconstruction of fetal body and placenta, rigid registration cannot resolve the issue of misregistrations due to deformable motion, resulting in degradation of features in the reconstructed volume. We propose a Deformable SVR (DSVR), a novel approach for non-rigid motion correction of fetal MRI based on a hierarchical deformable SVR scheme to allow high resolution reconstruction of the fetal body and placenta. Additionally, a robust scheme for structure-based rejection of outliers minimises the impact of registration errors. The improved performance of DSVR in comparison to SVR and patch-to-volume registration (PVR) methods is quantitatively demonstrated in simulated experiments and 20 fetal MRI datasets from 28-31 weeks gestational age (GA) range with varying degree of motion corruption. In addition, we present qualitative evaluation of 100 fetal body cases from 20-34 weeks GA range.